STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1724Putative surface-anchored membrane protein; No significant database matches. Note: Contains a potential sortase anchor site (LANTG) upstream of the C-terminal region transmembrane domain. Contains also a putative twin-arginine translocation (TAT) system recognition motif (RRVFAS) at the N-terminal region. Also similar to DIP0439, DIP0442, DIP2325 and DIP0443. (1075 aa)    
Predicted Functional Partners:
DIP0438
Putative secreted protein; C-terminal similar to Bacillus halodurans surface adhesin A precursor PsaA or BH0516 TR:Q9KFG3 (EMBL:AP001508) (300 aa) fasta scores: E(): 2.9e-14, 34.09% id in 176 aa; Belongs to the bacterial solute-binding protein 9 family.
 
   
 0.775
DIP0440
Similar to Deinococcus radiodurans manganese ABC transporter, ATP-binding protein, putative DR2284 TR:Q9RS43 (EMBL:AE002060) (239 aa) fasta scores: E(): 5.3e-25, 39.57% id in 235 aa.
 
   
 0.701
DIP0441
Putative membrane protein; Similar to Streptococcus gordonii challis 29 kDa membrane protein in psaA 5'region SW:P29K_STRGC (P42361) (278 aa) fasta scores: E(): 3.8e-28, 38.25% id in 264 aa.
 
   
 0.647
DIP1725
Similar to Mycobacterium tuberculosis putative long-chain-fatty-acid-CoA ligase FadD15 or Rv2187 or MTV021.20 TR:O53521 (EMBL:AL021957) (600 aa) fasta scores: E(): 9.3e-80, 46.48% id in 611 aa, and to Streptomyces coelicolor putative long chain fatty acid CoA ligase SC6G10.04 TR:Q9X7Z0 (EMBL:AL049497) (598 aa) fasta scores: E(): 1.7e-78, 46.72% id in 610 aa.
       0.563
hemN
Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
       0.486
DIP1723
Hypothetical protein; No significant database matches.
       0.486
DIP0439
Putative membrane protein; No significant database matches. Note: Also presents similarities with DIP1724, DIP0442, DIP2325 and DIP0443.
 
   
0.474
DIP1834
Putative phage protein; Similar to Bacteriophage r1t ORF40 TR:Q38126 (EMBL:U38906) (213 aa) fasta scores: E(): 0.019, 25.904% id in 166 aa, and to Escherichia coli O157:H7 putative tail length tape measure protein precursor ECS2949 TR:BAB36372 (EMBL:AP002560) (881 aa) fasta scores: E(): 0.025, 27.698% id in 278 aa.
  
     0.437
repA
Putative IS element transposase (pseudogene); Pseudogene. Similar to although shorter in its N-terminal region than Shigella flexneri putative transposase for IS110 S0128 SWALL:Q9AFS5 (EMBL:AF348706) (398 aa) fasta scores: E(): 1.6e-18, 40.55% id in 254 aa, and similar to Streptomyces coelicolor putative IS element transposase SC3C8.17 SWALL:O69929 (EMBL:AL023861) (230 aa) fasta scores: E(): 7.9e-18, 45.61% id in 171 aa. Presents multiple frameshifts at residues 84, 125, 130, 145, 150 and 180.
  
   
 0.437
DIP2153
Similar to Bacteriophage phi-105 holin TR:Q38456 (EMBL:L35561) (124 aa) fasta scores: E(): 5.4e-14, 41.22% id in 114 aa, and to Escherichia coli O157:H7 putative holin protein of prophage cp-933c Z1852 or ECS1595 TR:AAG55949 (EMBL:AE005328) (129 aa) fasta scores: E(): 1.7e-07, 40.77% id in 103 aa.
  
     0.421
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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