STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1725Similar to Mycobacterium tuberculosis putative long-chain-fatty-acid-CoA ligase FadD15 or Rv2187 or MTV021.20 TR:O53521 (EMBL:AL021957) (600 aa) fasta scores: E(): 9.3e-80, 46.48% id in 611 aa, and to Streptomyces coelicolor putative long chain fatty acid CoA ligase SC6G10.04 TR:Q9X7Z0 (EMBL:AL049497) (598 aa) fasta scores: E(): 1.7e-78, 46.72% id in 610 aa. (609 aa)    
Predicted Functional Partners:
fas
Putative fatty acid synthase; Similar to the N-terminal region of Corynebacterium ammoniagenes fatty acid synthase Fas TR:Q04846 (EMBL:X64795) (3104 aa) fasta scores: E(): 0, 61.33% id in 3018 aa, and to the full length of Mycobacterium tuberculosis fatty acid synthase Rv2524c TR:AAK46907 (EMBL:Z83863) (3069 aa) fasta scores: E(): 1e-197, 51.37% id in 3083 aa, and of Corynebacterium glutamicum 3-oxoacyl-(acyl-carrier-protein) synthase CGL2495 SWALL:Q8NMS0 (EMBL:AP005281) (2993 aa) fasta scores: E(): 0, 67.35% id in 3008 aa.
  
 0.989
DIP0386
Putative ligase; Similar to Escherichia coli long-chain-fatty-acid--CoA ligase FadD or OldD or B1805 SW:LCFA_ECOLI (P29212) (561 aa) fasta scores: E(): 7.5e-62, 34.46% id in 560 aa. Possible duplication of the downstream CDS: Similar to DIP0387 (566 aa) fasta scores: E(): 1.2e-164, 73.488% identity in 562 aa overlap.
 
 
0.925
DIP0387
Putative ligase; Similar to Escherichia coli long-chain-fatty-acid--CoA ligase FadD or OldD or B1805 SW:LCFA_ECOLI (P29212) (561 aa) fasta scores: E(): 7.8e-63, 34.69% id in 565 aa. Possible duplication of the upstream CDS: Similar to DIP0386 (568 aa) fasta scores: E(): 1.2e-164, 73.488% identity in 562 aa overlap.
 
 
0.924
ppm1
Similar to Mycobacterium smegmatis putative polyprenol phosphate mannosyl transferase 1 Ppm1 SWALL:Q9F408 (EMBL:AJ294477) (265 aa) fasta scores: E(): 1.6e-56, 61.6% id in 237 aa, and to Schizosaccharomyces pombe dolichol-phosphate mannosyltransferase Dpm1 or SPAC31G5.16c SWALL:O14466 (EMBL:AF007873) (236 aa) fasta scores: E(): 1.2e-24, 39.54% id in 220 aa.
  
   
 0.883
DIP1803
Similar to Mycobacterium tuberculosis ABC-transporter ATP binding protein MTV008.33c TR:O53204 (EMBL:AL021246) (558 aa) fasta scores: E(): 2.7e-143, 82.58% id in 557 aa, and to Mycobacterium leprae putative ABC transporter ATP-binding protein Rv2477c TR:Q9X7B1 (EMBL:AL049913) (556 aa) fasta scores: E(): 1.1e-140, 81.29% id in 556 aa.
   
  
 0.864
tesB
Putative acyl-CoA thioesterase II; Similar to Mycobacterium tuberculosis TesB or TesB2 or Rv2605c or MTCY01A10.28 SWALL:O06209 (EMBL:Z95387) (281 aa) fasta scores: E(): 1.9e-49, 50.17% id in 279 aa, and to Escherichia coli acyl-CoA thioesterase II TesB or B0452 or Z0564 or ECS0506 SWALL:TESB_ECOLI (SWALL:P23911) (285 aa) fasta scores: E(): 3e-20, 37.27% id in 279 aa.
   
 
 0.858
DIP1726
Putative glucanotransferase; Similar to Mycobacterium tuberculosis 4-alpha-glucanotransferase MalQ or Rv1781c or MT1831 or MTV049.03c SW:MALQ_MYCTU (O53932) (724 aa) fasta scores: E(): 7.8e-73, 45.87% id in 728 aa, and to Escherichia coli 4-alpha-glucanotransferase MalQ or MalA or B3416 SW:MALQ_ECOLI (P15977) (694 aa) fasta scores: E(): 1.2e-29, 28.48% id in 660 aa.
 
     0.732
DIP2160
Modular polyketide synthase; Similar to Streptomyces verticillus polyketide synthase BlmVIII (bleomycin biosynthesis) TR:Q9FB25 (EMBL:AF210249) (1841 aa) fasta scores: E(): 1.3e-72, 27.240% id in 1931 aa, and to Streptomyces noursei nystatin biosynthesis polyketide synthase Nys TR:Q9L4W3 (EMBL:AF263912) (11096 aa) fasta scores: E(): 4e-71, 33.107% id in 882 aa, and to Amycolatopsis mediterranei rifamycin polyketide synthase TR:Q9F847 (EMBL:AF262754) (1265 aa) fasta scores: E(): 7.7e-61, 31.042% id in 902 aa.
  
 
 0.667
rplE
50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
    
 
 0.622
DIP0358
Putative CoA-ligase; Similar to Mycobacterium tuberculosis CDC1551 substrate--CoA ligase, putative MT1470 TR:AAK45735 (EMBL:AE007017) (535 aa) fasta scores: E(): 8.6e-57, 36.1% id in 529 aa.
 
  
 0.599
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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