STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1729Putative drug resistance protein (hydrolase); Similar to Streptomyces coelicolor putative carboxylesterase SC5G9.30 TR:Q9RKZ7 (EMBL:AL117385) (518 aa) fasta scores: E(): 3.2e-14, 30.57% id in 363 aa, and to Bacillus subtilis para-nitrobenzyl esterase PnbA SW:PNBA_BACSU (P37967) (489 aa) fasta scores: E(): 7.3e-12, 28.22% id in 372 aa; Belongs to the type-B carboxylesterase/lipase family. (399 aa)    
Predicted Functional Partners:
DIP1728
Putative peptidase; Similar to Escherichia coli peptidyl-dipeptidase Dcp or B1538 SW:DCP_ECOLI (P24171) (680 aa) fasta scores: E(): 6.5e-63, 38.52% id in 680 aa, and to Escherichia coli oligopeptidase A PrlC or OpdA or B3498 SW:OPDA_ECOLI (P27298) (680 aa) fasta scores: E(): 1.8e-37, 31.35% id in 689 aa.
       0.711
rpsD
30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
    
  0.635
DIP1727
Putative membrane protein; No significant database matches.
       0.578
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
   
  0.556
rpsK
30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
    
  0.546
DIP1396
Putative ribonuclease; Similar to Mycobacterium tuberculosis CDC1551 ribonuclease D, putative MT2755 TR:AAK47070 (EMBL:AE007105) (438 aa) fasta scores: E(): 5.1e-49, 38.14% id in 409 aa, and to Escherichia coli ribonuclease D Rnd or B1804 SW:RND_ECOLI (P09155) (375 aa) fasta scores: E(): 1.2e-10, 28.36% id in 342 aa.
    
  0.519
DIP0896
Putative oxydoreductase; Similar to Streptomyces peucetius daunorubicin C-13 ketoreductase DnrU TR:Q9ZAU1 (EMBL:U77891) (287 aa) fasta scores: E(): 1.3e-16, 35.25% id in 278 aa.
  
 0.445
rpsL
30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.
  
  0.430
DIP0131
Similar to Escherichia coli ATP-dependent helicase HrpB or B0148 SW:HRPB_ECOLI (P37024) (809 aa) fasta scores: E(): 2.6e-40, 35.09% id in 815 aa.
    
  0.428
DIP1423
Similar to Escherichia coli ATP-dependent helicase HrpA or B1413 SW:HRPA_ECOLI (P43329) (1300 aa) fasta scores: E(): 1.7e-172, 46.92% id in 1315 aa, and to Vibrio cholerae ATP-dependent helicase HrpA VC1382 TR:Q9KS77 (EMBL:AE004217) (1309 aa) fasta scores: E(): 2.3e-171, 47.6% id in 1317 aa.
    
  0.428
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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