STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1729Putative drug resistance protein (hydrolase); Similar to Streptomyces coelicolor putative carboxylesterase SC5G9.30 TR:Q9RKZ7 (EMBL:AL117385) (518 aa) fasta scores: E(): 3.2e-14, 30.57% id in 363 aa, and to Bacillus subtilis para-nitrobenzyl esterase PnbA SW:PNBA_BACSU (P37967) (489 aa) fasta scores: E(): 7.3e-12, 28.22% id in 372 aa; Belongs to the type-B carboxylesterase/lipase family. (399 aa)    
Predicted Functional Partners:
DIP1728
Putative peptidase; Similar to Escherichia coli peptidyl-dipeptidase Dcp or B1538 SW:DCP_ECOLI (P24171) (680 aa) fasta scores: E(): 6.5e-63, 38.52% id in 680 aa, and to Escherichia coli oligopeptidase A PrlC or OpdA or B3498 SW:OPDA_ECOLI (P27298) (680 aa) fasta scores: E(): 1.8e-37, 31.35% id in 689 aa.
       0.697
DIP1727
Putative membrane protein; No significant database matches.
       0.571
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
  0.489
DIP0896
Putative oxydoreductase; Similar to Streptomyces peucetius daunorubicin C-13 ketoreductase DnrU TR:Q9ZAU1 (EMBL:U77891) (287 aa) fasta scores: E(): 1.3e-16, 35.25% id in 278 aa.
  
 0.460
DIP0303
Putative transcription regulator; Similar to Corynebacterium glutamicum probable transcription regulator TR:AAK58838 (EMBL:AF293334) (227 aa) fasta scores: E(): 8e-79, 91.18% id in 227 aa, and to Escherichia coli catabolite gene activator Crp or Cap or Csm or B3357 or Z4718 or ECS4208 SW:CRP_ECOLI (P03020) (210 aa) fasta scores: E(): 4.6e-15, 33.68% id in 190 aa.
   
   0.433
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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