Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
DIP1738Conserved hypothetical protein; Similar to Agrobacterium tumefaciens StrC58 AGR_l_2217p TR:AAK89679 (EMBL:AE008310) (333 aa) fasta scores: E(): 5.1e-42, 45.79% id in 321 aa. (317 aa)    
Predicted Functional Partners:
brnQ
Branched-chain amino acid ABC transport system membrane protein; Component of the transport system for branched-chain amino acids.
     
 0.834
DIP0292
Similar to Staphylococcus aureus Na+/H+-antiporter subunit MnhC or SA0811 TR:Q9ZNG4 (EMBL:AB015981) (113 aa) fasta scores: E(): 6.5e-08, 38.889% id in 90 aa.
      
 0.694
aecD
Beta C-S lyase; Similar to Corynebacterium glutamicum beta C-S lyase AecD TR:Q46061 (EMBL:M89931) (325 aa) fasta scores: E(): 3e-66, 53.93% id in 330 aa.
       0.683
DIP1735
Putative ABC transport system ATP-binding membrane protein; Similar to Amycolatopsis orientalis hypothetical 71.1 kDa protein PCZA363.2 CZA382.30 TR:O52818 (EMBL:AJ223999) (650 aa) fasta scores: E(): 1.8e-39, 30.58% id in 618 aa.
       0.659
DIP2189
Putative polyketide synthase; Similar to Mycobacterium tuberculosis polyketide synthase PKS13 or Rv3800c or MTV026.05c TR:O53579 (EMBL:AL022076) (1733 aa) fasta scores: E(): 5.4e-109, 44.5% id in 1719 aa, and to Polyangium cellulosum soraphen polyketide synthase A SorA TR:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 6.2e-101, 35.96% id in 1090 aa.
     
 0.578
DIP1734
Hypothetical protein; No significant database matches.
       0.543
DIP0632
Putative membrane protein; Similar to Rhizobium meliloti putative transport transmembrane protein SMC02161 TR:CAC41922 (EMBL:AL591783) (411 aa) fasta scores: E(): 5.7e-56, 46.61% id in 384 aa, and to Streptomyces coelicolor putative transmembrane efflux protein SC1G2.16c TR:Q9RDR3 (EMBL:AL136500) (413 aa) fasta scores: E(): 4.7e-46, 41.62% id in 370 aa.
  
     0.494
DIP2160
Modular polyketide synthase; Similar to Streptomyces verticillus polyketide synthase BlmVIII (bleomycin biosynthesis) TR:Q9FB25 (EMBL:AF210249) (1841 aa) fasta scores: E(): 1.3e-72, 27.240% id in 1931 aa, and to Streptomyces noursei nystatin biosynthesis polyketide synthase Nys TR:Q9L4W3 (EMBL:AF263912) (11096 aa) fasta scores: E(): 4e-71, 33.107% id in 882 aa, and to Amycolatopsis mediterranei rifamycin polyketide synthase TR:Q9F847 (EMBL:AF262754) (1265 aa) fasta scores: E(): 7.7e-61, 31.042% id in 902 aa.
     
 0.488
idi
Isopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
       0.434
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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