STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1765Conserved hypothetical protein; Poor database matches. C-terminal region is similar to Mycobacterium tuberculosis hypothetical protein Rv2405 TR:P71738 (EMBL:Z81368) (189 aa) fasta scores: E(): 1.9e-22, 43.7% id in 135 aa. Possible alternative translational start site. (185 aa)    
Predicted Functional Partners:
rpsT
30S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
       0.648
lepA
Putative GTP-binding protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
       0.620
DIP0622
Putative membrane protein; No significant database matches.
  
    0.470
DIP1733
Hypothetical protein; No significant database matches.
  
     0.464
DIP0899
Conserved hypothetical protein; Low similarity to parts of Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT0103 TR:AAK44326 (EMBL:AE006921) (287 aa) fasta scores: E(): 5.6e-09, 39.04% id in 105 aa.
  
    0.407
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.