STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1773Similar to Mycobacterium leprae possible phosphoglycerate mutase ML1452 TR:Q9CC00 (EMBL:AL583922) (224 aa) fasta scores: E(): 1.1e-34, 44.26% id in 244 aa, and to Mycobacterium tuberculosis hypothetical protein Rv2419c TR:P71724 (EMBL:Z81368) (223 aa) fasta scores: E(): 6.3e-34, 52.88% id in 191 aa. (240 aa)    
Predicted Functional Partners:
DIP1772
Similar to Mycobacterium tuberculosis hypothetical protein Rv2417c TR:P71726 (EMBL:Z81368) (280 aa) fasta scores: E(): 1e-21, 34.92% id in 272 aa, and to Streptomyces coelicolor hypothetical protein SCC123.07c TR:Q9RDL7 (EMBL:AL136518) (281 aa) fasta scores: E(): 6e-21, 36.13% id in 274 aa.
  
  
 0.912
rsfS
Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
    0.853
nadD
Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
    0.819
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
       0.763
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
       0.742
DIP0985
Conserved hypothetical protein; Similar to Streptomyces coelicolor hypothetical 34.0 kDa protein SCD95A.25c TR:Q9KXU9 (EMBL:AL357432) (314 aa) fasta scores: E(): 2.9e-29, 47.67% id in 258 aa, and to Methanothermobacter thermautotrophicus dolichyl-phosphate mannose synthase related protein MTH374 TR:O26474 (EMBL:AE000823) (291 aa) fasta scores: E(): 1.4e-08, 31.89% id in 254 aa.
   
 0.722
obg
GTP1/OBG-family GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
       0.716
DIP1768
Conserved hypothetical protein; Similar to Streptomyces coelicolor putative ankyrin-like protein SC6D7.25 TR:Q9RKX3 (EMBL:AL133213) (134 aa) fasta scores: E(): 4.4e-23, 57.36% id in 129 aa, and to Campylobacter jejuni ankyrin-repeat containing protein Cj1386 TR:Q9PMR4 (EMBL:AL139078) (156 aa) fasta scores: E(): 1.2e-10, 39.66% id in 121 aa.
   
 
 0.701
DIP1767
Putative LysE type translocator; Similar to Escherichia coli threonine efflux protein RhtC SW:RHTC_ECOLI (P27846) (206 aa) fasta scores: E(): 2.7e-18, 30.43% id in 207 aa, and to Salmonella typhimurium LT2 putative threonine efflux protein RhtC TR:Q9L6N7 (EMBL:AF233324) (206 aa) fasta scores: E(): 1.7e-18, 30.88% id in 204 aa.
  
    0.684
DIP1769
Similar to Mycobacterium tuberculosis hypothetical protein Rv2413c TR:AAK46782 (EMBL:Z81368) (322 aa) fasta scores: E(): 1.9e-40, 42.63% id in 319 aa, and to Streptomyces coelicolor putative DNA-binding protein SCC123.02c TR:Q9RDM2 (EMBL:AL136518) (336 aa) fasta scores: E(): 6.3e-33, 37.69% id in 321 aa.
       0.682
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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