Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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ndkPutative nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (144 aa)    
Predicted Functional Partners:
rpsJ
30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
   
  0.966
rpsG
30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
   
  0.965
rpsO
30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
  
  0.963
rpsL
30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.
   
  0.942
rpsB
30S ribosomal protein S2; Similar to Mycobacterium tuberculosis 30S ribosomal protein S2 RpsB or Rv2890c or MT2958 or MTCY274.21c SW:RS2_MYCTU (Q10796) (287 aa) fasta scores: E(): 1.4e-68, 70.94% id in 265 aa, and to Escherichia coli 30S ribosomal protein S2 RpsB or B0169 or Z0180 or ECS0171 SW:RS2_ECOLI (P02351) (240 aa) fasta scores: E(): 2.8e-40, 50.22% id in 225 aa; Belongs to the universal ribosomal protein uS2 family.
   
 0.939
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
   
 
 0.938
rpsK
30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
   
 0.933
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
 
 0.929
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
   
 
 0.927
cmk
Cytidylate kinase; Similar to Mycobacterium tuberculosis cytidylate kinase Cmk or Rv1712 or MT1752 or MTCI125.34 SWALL:KCY_MYCTU (SWALL:O33211) (230 aa) fasta scores: E(): 1.9e-35, 55.45% id in 220 aa, and to Escherichia coli cytidylate kinase Cmk or MssA or B0910 or Z1256 or ECS0993 SWALL:KCY_ECOLI (SWALL:P23863) (227 aa) fasta scores: E(): 9.7e-25, 43.54% id in 209 aa.
  
 
 0.925
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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