Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DIP1926 | clpP1 | DIP1926 | DIP1792 | Putative prolyl oligopeptidase; Similar to Mycobacterium tuberculosis CDC1551 protease II MT0805 TR:AAK45047 (EMBL:AE006971) (718 aa) fasta scores: E(): 1.1e-159, 55.68% id in 695 aa, and to Mycobacterium leprae ML2226 TR:O05748 (EMBL:Z95151) (724 aa) fasta scores: E(): 8.2e-148, 52.36% id in 699 aa. | ATP-dependent Clp protease proteolytic subunit 1; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.875 |
| DIP1926 | clpP2 | DIP1926 | DIP1791 | Putative prolyl oligopeptidase; Similar to Mycobacterium tuberculosis CDC1551 protease II MT0805 TR:AAK45047 (EMBL:AE006971) (718 aa) fasta scores: E(): 1.1e-159, 55.68% id in 695 aa, and to Mycobacterium leprae ML2226 TR:O05748 (EMBL:Z95151) (724 aa) fasta scores: E(): 8.2e-148, 52.36% id in 699 aa. | ATP-dependent Clp protease proteolytic subunit 2; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.588 |
| clpB | clpP1 | DIP2104 | DIP1792 | Putative ATP-dependent protease regulatory subunit, ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity). Belong [...] | ATP-dependent Clp protease proteolytic subunit 1; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.821 |
| clpB | clpP2 | DIP2104 | DIP1791 | Putative ATP-dependent protease regulatory subunit, ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity). Belong [...] | ATP-dependent Clp protease proteolytic subunit 2; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.815 |
| clpB | dnaK | DIP2104 | DIP2120 | Putative ATP-dependent protease regulatory subunit, ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity). Belong [...] | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.992 |
| clpB | hrcA | DIP2104 | DIP1721 | Putative ATP-dependent protease regulatory subunit, ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity). Belong [...] | Putative heat-inducible transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.526 |
| clpB2 | clpP1 | DIP2101 | DIP1792 | Putative heat shock protein (partial); Similar to Corynebacterium glutamicum ClpB protein SWALL:CLPB_CORGL (SWALL:P53532) (852 aa) fasta scores: E(): 0.027, 44.44% id in 99 aa, and to Mycobacterium leprae heat shock protein ClpB or ML2490 SWALL:Q9CB26 (EMBL:AL583925) (848 aa) fasta scores: E(): 0.66, 35.41% id in 96 aa. Note: Similar also to the C-terminal part of DIP2104 (849 aa) E(): 7.2e-08; 53.465% identity in 101 aa overlap. | ATP-dependent Clp protease proteolytic subunit 1; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.821 |
| clpB2 | clpP2 | DIP2101 | DIP1791 | Putative heat shock protein (partial); Similar to Corynebacterium glutamicum ClpB protein SWALL:CLPB_CORGL (SWALL:P53532) (852 aa) fasta scores: E(): 0.027, 44.44% id in 99 aa, and to Mycobacterium leprae heat shock protein ClpB or ML2490 SWALL:Q9CB26 (EMBL:AL583925) (848 aa) fasta scores: E(): 0.66, 35.41% id in 96 aa. Note: Similar also to the C-terminal part of DIP2104 (849 aa) E(): 7.2e-08; 53.465% identity in 101 aa overlap. | ATP-dependent Clp protease proteolytic subunit 2; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.815 |
| clpB2 | dnaK | DIP2101 | DIP2120 | Putative heat shock protein (partial); Similar to Corynebacterium glutamicum ClpB protein SWALL:CLPB_CORGL (SWALL:P53532) (852 aa) fasta scores: E(): 0.027, 44.44% id in 99 aa, and to Mycobacterium leprae heat shock protein ClpB or ML2490 SWALL:Q9CB26 (EMBL:AL583925) (848 aa) fasta scores: E(): 0.66, 35.41% id in 96 aa. Note: Similar also to the C-terminal part of DIP2104 (849 aa) E(): 7.2e-08; 53.465% identity in 101 aa overlap. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.982 |
| clpB2 | hrcA | DIP2101 | DIP1721 | Putative heat shock protein (partial); Similar to Corynebacterium glutamicum ClpB protein SWALL:CLPB_CORGL (SWALL:P53532) (852 aa) fasta scores: E(): 0.027, 44.44% id in 99 aa, and to Mycobacterium leprae heat shock protein ClpB or ML2490 SWALL:Q9CB26 (EMBL:AL583925) (848 aa) fasta scores: E(): 0.66, 35.41% id in 96 aa. Note: Similar also to the C-terminal part of DIP2104 (849 aa) E(): 7.2e-08; 53.465% identity in 101 aa overlap. | Putative heat-inducible transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.526 |
| clpC | clpP1 | DIP1983 | DIP1792 | ATP-dependent Clp protease ATP-binding subunit; Similar to Bacillus subtilis negative regulator of genetic competence ClpC SW:CLPC_BACSU (P37571) (810 aa) fasta scores: E(): 2.6e-134, 58.11% id in 826 aa, and to Mycobacterium tuberculosis probable ATP-dependent Clp protease ATP-binding subunit Rv3596c SW:CLPC_MYCTU (O06286) (848 aa) fasta scores: E(): 1.7e-186, 81.81% id in 847 aa; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease proteolytic subunit 1; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.979 |
| clpC | clpP2 | DIP1983 | DIP1791 | ATP-dependent Clp protease ATP-binding subunit; Similar to Bacillus subtilis negative regulator of genetic competence ClpC SW:CLPC_BACSU (P37571) (810 aa) fasta scores: E(): 2.6e-134, 58.11% id in 826 aa, and to Mycobacterium tuberculosis probable ATP-dependent Clp protease ATP-binding subunit Rv3596c SW:CLPC_MYCTU (O06286) (848 aa) fasta scores: E(): 1.7e-186, 81.81% id in 847 aa; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease proteolytic subunit 2; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.976 |
| clpC | clpX | DIP1983 | DIP1789 | ATP-dependent Clp protease ATP-binding subunit; Similar to Bacillus subtilis negative regulator of genetic competence ClpC SW:CLPC_BACSU (P37571) (810 aa) fasta scores: E(): 2.6e-134, 58.11% id in 826 aa, and to Mycobacterium tuberculosis probable ATP-dependent Clp protease ATP-binding subunit Rv3596c SW:CLPC_MYCTU (O06286) (848 aa) fasta scores: E(): 1.7e-186, 81.81% id in 847 aa; Belongs to the ClpA/ClpB family. | Putative ATPase; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.776 |
| clpC | dnaK | DIP1983 | DIP2120 | ATP-dependent Clp protease ATP-binding subunit; Similar to Bacillus subtilis negative regulator of genetic competence ClpC SW:CLPC_BACSU (P37571) (810 aa) fasta scores: E(): 2.6e-134, 58.11% id in 826 aa, and to Mycobacterium tuberculosis probable ATP-dependent Clp protease ATP-binding subunit Rv3596c SW:CLPC_MYCTU (O06286) (848 aa) fasta scores: E(): 1.7e-186, 81.81% id in 847 aa; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.959 |
| clpC | hrcA | DIP1983 | DIP1721 | ATP-dependent Clp protease ATP-binding subunit; Similar to Bacillus subtilis negative regulator of genetic competence ClpC SW:CLPC_BACSU (P37571) (810 aa) fasta scores: E(): 2.6e-134, 58.11% id in 826 aa, and to Mycobacterium tuberculosis probable ATP-dependent Clp protease ATP-binding subunit Rv3596c SW:CLPC_MYCTU (O06286) (848 aa) fasta scores: E(): 1.7e-186, 81.81% id in 847 aa; Belongs to the ClpA/ClpB family. | Putative heat-inducible transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.688 |
| clpP1 | DIP1926 | DIP1792 | DIP1926 | ATP-dependent Clp protease proteolytic subunit 1; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Putative prolyl oligopeptidase; Similar to Mycobacterium tuberculosis CDC1551 protease II MT0805 TR:AAK45047 (EMBL:AE006971) (718 aa) fasta scores: E(): 1.1e-159, 55.68% id in 695 aa, and to Mycobacterium leprae ML2226 TR:O05748 (EMBL:Z95151) (724 aa) fasta scores: E(): 8.2e-148, 52.36% id in 699 aa. | 0.875 |
| clpP1 | clpB | DIP1792 | DIP2104 | ATP-dependent Clp protease proteolytic subunit 1; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Putative ATP-dependent protease regulatory subunit, ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity). Belong [...] | 0.821 |
| clpP1 | clpB2 | DIP1792 | DIP2101 | ATP-dependent Clp protease proteolytic subunit 1; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Putative heat shock protein (partial); Similar to Corynebacterium glutamicum ClpB protein SWALL:CLPB_CORGL (SWALL:P53532) (852 aa) fasta scores: E(): 0.027, 44.44% id in 99 aa, and to Mycobacterium leprae heat shock protein ClpB or ML2490 SWALL:Q9CB26 (EMBL:AL583925) (848 aa) fasta scores: E(): 0.66, 35.41% id in 96 aa. Note: Similar also to the C-terminal part of DIP2104 (849 aa) E(): 7.2e-08; 53.465% identity in 101 aa overlap. | 0.821 |
| clpP1 | clpC | DIP1792 | DIP1983 | ATP-dependent Clp protease proteolytic subunit 1; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATP-dependent Clp protease ATP-binding subunit; Similar to Bacillus subtilis negative regulator of genetic competence ClpC SW:CLPC_BACSU (P37571) (810 aa) fasta scores: E(): 2.6e-134, 58.11% id in 826 aa, and to Mycobacterium tuberculosis probable ATP-dependent Clp protease ATP-binding subunit Rv3596c SW:CLPC_MYCTU (O06286) (848 aa) fasta scores: E(): 1.7e-186, 81.81% id in 847 aa; Belongs to the ClpA/ClpB family. | 0.979 |
| clpP1 | clpP2 | DIP1792 | DIP1791 | ATP-dependent Clp protease proteolytic subunit 1; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATP-dependent Clp protease proteolytic subunit 2; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.999 |
page 1 of 4