STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1799Putative mechanosensitive ion channel protein; C-terminus is similar to thye C-terminal region of Streptomyces coelicolor hypothetical protein SCF43A.26C TR:Q9XA89 (EMBL:AL096837) (333 aa) fasta scores: E(): 1.4e-38, 41.75% id in 297 aa. Similar to an internal region of Streptomyces coelicolor putative membrane protein SC8E4A.26 TR:Q9L1X9 (EMBL:AL138662) (408 aa) fasta scores: E(): 2.7e-28, 38.41% id in 302 aa. (338 aa)    
Predicted Functional Partners:
DIP1800
Putative hemoglobin; Similar to Mycobacterium tuberculosis hemoglobin-like protein Rv2470 TR:O53197 (EMBL:AL021246) (128 aa) fasta scores: E(): 6.5e-24, 51.61% id in 124 aa, and to Mycobacterium leprae hemoglobin-like protein ML1253 TR:Q9CC59 (EMBL:AL583921) (128 aa) fasta scores: E(): 5.9e-23, 50.8% id in 124 aa.
       0.780
DIP1798
Putative aminopeptidase; Similar to Streptomyces lividans aminopeptidase N PepN SW:AMPN_STRLI (Q11010) (857 aa) fasta scores: E(): 1.2e-88, 45.27% id in 888 aa, and to Mycobacterium tuberculosis aminopeptidase Rv2467 TR:O53194 (EMBL:AL021246) (861 aa) fasta scores: E(): 1.9e-132, 51.97% id in 885 aa. CDS appears to be extended at the N-terminus in comparison to orthologues. Possible alternative translational start site, although current start has better RBS and extented region contains Pfam hit.
  
    0.486
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.