STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1800Putative hemoglobin; Similar to Mycobacterium tuberculosis hemoglobin-like protein Rv2470 TR:O53197 (EMBL:AL021246) (128 aa) fasta scores: E(): 6.5e-24, 51.61% id in 124 aa, and to Mycobacterium leprae hemoglobin-like protein ML1253 TR:Q9CC59 (EMBL:AL583921) (128 aa) fasta scores: E(): 5.9e-23, 50.8% id in 124 aa. (130 aa)    
Predicted Functional Partners:
DIP1799
Putative mechanosensitive ion channel protein; C-terminus is similar to thye C-terminal region of Streptomyces coelicolor hypothetical protein SCF43A.26C TR:Q9XA89 (EMBL:AL096837) (333 aa) fasta scores: E(): 1.4e-38, 41.75% id in 297 aa. Similar to an internal region of Streptomyces coelicolor putative membrane protein SC8E4A.26 TR:Q9L1X9 (EMBL:AL138662) (408 aa) fasta scores: E(): 2.7e-28, 38.41% id in 302 aa.
       0.780
DIP0532
Putative amylase; Similar to Streptomyces coelicolor alpha-glucosidase AglA TR:Q9KZ09 (EMBL:AL355752) (577 aa) fasta scores: E(): 2.2e-97, 48.09% id in 578 aa.
      0.690
DIP1798
Putative aminopeptidase; Similar to Streptomyces lividans aminopeptidase N PepN SW:AMPN_STRLI (Q11010) (857 aa) fasta scores: E(): 1.2e-88, 45.27% id in 888 aa, and to Mycobacterium tuberculosis aminopeptidase Rv2467 TR:O53194 (EMBL:AL021246) (861 aa) fasta scores: E(): 1.9e-132, 51.97% id in 885 aa. CDS appears to be extended at the N-terminus in comparison to orthologues. Possible alternative translational start site, although current start has better RBS and extented region contains Pfam hit.
       0.610
DIP1797
Similar to Mycobacterium tuberculosis hypothetical protein Rv2466c TR:O53193 (EMBL:AL021246) (207 aa) fasta scores: E(): 2.5e-43, 57.63% id in 203 aa, and to Mycobacterium leprae hypothetical protein ML1485 TR:Q9CBY0 (EMBL:AL583922) (207 aa) fasta scores: E(): 1.7e-40, 55.94% id in 202 aa.
 
     0.422
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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