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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1803Similar to Mycobacterium tuberculosis ABC-transporter ATP binding protein MTV008.33c TR:O53204 (EMBL:AL021246) (558 aa) fasta scores: E(): 2.7e-143, 82.58% id in 557 aa, and to Mycobacterium leprae putative ABC transporter ATP-binding protein Rv2477c TR:Q9X7B1 (EMBL:AL049913) (556 aa) fasta scores: E(): 1.1e-140, 81.29% id in 556 aa. (556 aa)    
Predicted Functional Partners:
ppm1
Similar to Mycobacterium smegmatis putative polyprenol phosphate mannosyl transferase 1 Ppm1 SWALL:Q9F408 (EMBL:AJ294477) (265 aa) fasta scores: E(): 1.6e-56, 61.6% id in 237 aa, and to Schizosaccharomyces pombe dolichol-phosphate mannosyltransferase Dpm1 or SPAC31G5.16c SWALL:O14466 (EMBL:AF007873) (236 aa) fasta scores: E(): 1.2e-24, 39.54% id in 220 aa.
  
   
 0.877
DIP1725
Similar to Mycobacterium tuberculosis putative long-chain-fatty-acid-CoA ligase FadD15 or Rv2187 or MTV021.20 TR:O53521 (EMBL:AL021957) (600 aa) fasta scores: E(): 9.3e-80, 46.48% id in 611 aa, and to Streptomyces coelicolor putative long chain fatty acid CoA ligase SC6G10.04 TR:Q9X7Z0 (EMBL:AL049497) (598 aa) fasta scores: E(): 1.7e-78, 46.72% id in 610 aa.
   
  
 0.864
rplW
50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.
  
   0.802
rpsE
30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.
  
   0.796
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
   
   0.782
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.780
rpsC
30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
   
   0.780
rpsO
30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
   
   0.780
rplD
50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
   
 
 0.779
rplM
50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
   0.779
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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