Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
DIP1805Putative membrane protein; Similar to Mycobacterium leprae hypothetical protein ML1998 SW:Y102_MYCLE (P53525) (659 aa) fasta scores: E(): 2e-44, 31.72% id in 665 aa, and to Mycobacterium tuberculosis hypothetical protein Rv0102 SW:Y102_MYCTU (Q10897) (661 aa) fasta scores: E(): 2.2e-44, 30.76% id in 650 aa. (678 aa)    
Predicted Functional Partners:
qcrC
Ubiquinol-cytochrome C reductase cytochrome C subunit; Cytochrome c1 subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
 
  
 0.883
DIP1391
Putative membrane protein; No significant database matches.
 
  
 0.872
qcrA
Ubiquinol-cytochrome C reductase iron-sulfur protein; Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis; Belongs to the Rieske iron-sulfur protein family.
 
    0.746
DIP0413
Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 57.1 kDa protein Rv0528 or MTCY25D10.07 TR:O06394 (EMBL:Z95558) (529 aa) fasta scores: E(): 3.9e-103, 49.43% id in 532 aa.
  
    0.738
DIP1300
Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 32.4 kDa protein Rv1456c or MT1503 or MTV007.03C SWALL:AAK45767 (EMBL:AL021184) (311 aa) fasta scores: E(): 3.7e-43, 43.75% id in 304 aa, and to Streptomyces coelicolor putative integral membrane transport protein SCC22.12 SWALL:Q9XAC6 (EMBL:AL096839) (356 aa) fasta scores: E(): 6.9e-24, 33.01% id in 312 aa, and low similarity to Bacillus firmus cytochrome aa3 controlling protein ctaA SWALL:CTAA_BACFI (SWALL:Q04443) (297 aa) fasta scores: E(): 0.0021, 21.42% id in 266 aa.
 
   
 0.734
DIP1684
Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 29.8 kDa protein Rv2235 precursor or MT2294 or MTCY427.16 SW:YM35_MYCTU (Q10517) (271 aa) fasta scores: E(): 1.4e-34, 38.54% id in 275 aa.
 
     0.698
sigC
Similar to Mycobacterium tuberculosis probable RNA polymerase sigma-C factor SigC or Rv2069 or MT2129 or MTCY49.08 SW:RPSC_MYCTU (Q10679) (185 aa) fasta scores: E(): 6.1e-30, 52.24% id in 178 aa; Belongs to the sigma-70 factor family. ECF subfamily.
      
 0.692
DIP1801
Conserved hypothetical protein; Limited database matches. Similar to Mycobacterium tuberculosis hypothetical protein Rv2474c TR:O53201 (EMBL:AL021246) (217 aa) fasta scores: E(): 2.2e-14, 39.59% id in 197 aa.
 
     0.630
DIP1643
Putative membrane protein; Similar to Streptomyces coelicolor putative integral membrane protein SC3H12.05c TR:Q9S2N9 (EMBL:AL355740) (155 aa) fasta scores: E(): 6.1e-16, 43.04% id in 151 aa.
  
     0.619
DIP0424
Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 18.7 kDa protein Rv0556 or MTCY25D10.35 TR:O06422 (EMBL:Z95558) (171 aa) fasta scores: E(): 1.2e-11, 42.14% id in 121 aa.
  
     0.617
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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