STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ornOligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family. (210 aa)    
Predicted Functional Partners:
DIP1812
Putative short chain dehydrogenase; Similar to Mycobacterium tuberculosis hypothetical protein Rv2509 TR:O06172 (EMBL:Z95556) (268 aa) fasta scores: E(): 1.3e-46, 52.25% id in 266 aa, and to Mycobacterium leprae dehydrogenase MLCl383.36c TR:O07709 (EMBL:Z97179) (268 aa) fasta scores: E(): 1.8e-44, 50.56% id in 265 aa; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
    0.811
DIP1475
Conserved hypothetical protein; Similar to, although shorter in its N-terminal region than, Mycobacterium tuberculosis hypothetical 35.4 kDa protein Rv2837c or MTCY16B7.05 TR:P71615 (EMBL:Z81331) (336 aa) fasta scores: E(): 8.5e-29, 34.84% id in 287 aa, and to Clostridium acetobutylicum exopolyphosphatase family protein CAC1804 TR:AAK79769 (EMBL:AE007689) (321 aa) fasta scores: E(): 1.9e-19, 33.19% id in 235 aa.
     
 0.769
DIP2368
Putative tRNA nucleotidyltransferase; Similar to a family of proteins from both prokaryotes and eukaryotes and including poly A polymerases and tRNA nucleotidyl transferases. Since prokaryotes don't generally have poly A tailed mRNAs the prokaryotic proteins are likely to be RNA nucleotidyl transferases. Similar to Mycobacterium tuberculosis PcnA or Rv3907c or MTCY15F10.04 TR:O05438 (EMBL:Z94121) (480 aa) fasta scores: E(): 3.5e-119, 64.61% id in 472 aa, and to Streptomyces coelicolor putative RNA nucleotidyltransferase SCH24.18 TR:Q9X8T2 (EMBL:AL049826) (483 aa) fasta scores: E(): 1.3 [...]
 
   
 0.674
rph
Putative ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
   
  
 0.612
DIP0826
Putative sulfite synthesis related protein; Similar to Mycobacterium tuberculosis CysQ protein homolog or Rv2131c or MT2189 or MTCY270.37 SW:CYSQ_MYCTU (O06244) (267 aa) fasta scores: E(): 9.2e-23, 52.51% id in 259 aa.
      
 0.597
rnj
Conserved hypothetical protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
      
 0.596
DIP1811
Similar to Rhizobium loti dehydrogenase; zinc-binding alcohol dehydrogenase; NADPH quinone oxidoreductase; oxidoreductase MLR3212 TR:Q98GR0 (EMBL:AP003001) (329 aa) fasta scores: E(): 4.7e-52, 47.67% id in 323 aa, and to Pseudomonas aeruginosa probable oxidoreductase PA1833 TR:Q9I2R2 (EMBL:AE004609) (330 aa) fasta scores: E(): 5.9e-45, 43.82% id in 324 aa.
       0.552
infC
Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
      
 0.491
gpsI
Guanosine pentaphosphate synthetase/ polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
      
 0.473
DIP1814
Similar to Corynebacterium glutamicum dihydrodipicolinate synthase DapA SW:DAPA_CORGL (P19808) (301 aa) fasta scores: E(): 7.7e-14, 29.25% id in 270 aa, and to Streptomyces coelicolor dihydrodipicolinate synthase SC9A10.08 SW:DAPA_STRCO (O86841) (299 aa) fasta scores: E(): 2.5e-13, 27.94% id in 272 aa; Belongs to the DapA family.
       0.473
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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