STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bcpSimilar to Escherichia coli bacterioferritin comigratory protein Bcp SW:BCP_ECOLI (P23480) (156 aa) fasta scores: E(): 7e-23, 46.8% id in 141 aa, and to Mycobacterium tuberculosis bacterioferritin comigratory protein Rv2521 TR:O53226 (EMBL:AL021185) (157 aa) fasta scores: E(): 3.5e-37, 62.17% id in 156 aa. (157 aa)    
Predicted Functional Partners:
DIP1844
Putative TetR-family regulatory protein; Similar to Rhizobium loti transcriptional regulator MLL3939 TR:Q98F48 (EMBL:AP003003) (209 aa) fasta scores: E(): 4.6e-12, 33.65% id in 208 aa, and to Pseudomonas aeruginosa probable transcriptional regulator PA1403 TR:Q9I3U1 (EMBL:AE004569) (210 aa) fasta scores: E(): 2e-05, 27.57% id in 214 aa.
       0.836
tmk
Putative thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
   
   0.731
DIP1842
Putative membrane protein; Poor database matches. Similar to Mycobacterium tuberculosis hypothetical protein Rv2520c TR:O53225 (EMBL:AL021185) (75 aa) fasta scores: E(): 2.7e-06, 45.33% id in 75 aa.
       0.685
trxA
Thioredoxin; Similar to Mycobacterium smegmatis thioredoxin TrxA SW:THIO_MYCSM (O30974) (112 aa) fasta scores: E(): 5.8e-18, 48.14% id in 108 aa; Belongs to the thioredoxin family.
   
 
 0.623
dirA
Almost identical to previously sequenced Corynebacterium diphtheriae iron repressible polypeptide DirA TR:Q46025 (EMBL:U18620) (198 aa) fasta scores: E(): 8.8e-79, 98.99% id in 198 aa, and to Mycobacterium smegmatis alkyl hydroperoxide reductase C AhpC TR:Q57529 (EMBL:U43719) (195 aa) fasta scores: E(): 5.2e-52, 66.12% id in 186 aa.
 
 
0.544
DIP1841
Similar to Mycobacterium tuberculosis hypothetical protein Rv3592 TR:O06156 (EMBL:Z95555) (105 aa) fasta scores: E(): 1.5e-21, 58.16% id in 98 aa, and to Mycobacterium leprae hypothetical protein ML1922 TR:Q9CBI8 (EMBL:AL583923) (105 aa) fasta scores: E(): 5.5e-19, 53.46% id in 101 aa.
       0.538
DIP0997
Putative ATP-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
  
  
 0.501
DIP0101
Putative membrane protein; Similar to Mycobacterium tuberculosis DipZ protein Rv2874 or MT2942 or MTCY274.05 SW:DIPZ_MYCTU (Q10801) (695 aa) fasta scores: E(): 1.6e-43, 43.65% id in 591 aa.
  
  
 0.497
DIP2284
Putative thioredoxin; Similar to Streptomyces coelicolor thioredoxin TrxA2 SWALL:Q9RD25 (EMBL:AL133422) (134 aa) fasta scores: E(): 1.7e-23, 52.89% id in 121 aa, and to Escherichia coli thioredoxin 2 TrxC or B2582 or Z3867 or ECS3448 SWALL:THI2_ECOLI (SWALL:P33636) (139 aa) fasta scores: E(): 5.9e-11, 38% id in 100 aa; Belongs to the thioredoxin family.
   
 
 0.474
ribD
Putative riboflavin biosynthesis protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.441
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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