STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1860Acetyltransferase (GNAT) family protein; Similar to Streptomyces coelicolor putative acetyltransferase SCC46.14 TR:Q9L1I8 (EMBL:AL139164) (202 aa) fasta scores: E(): 1.3e-08, 28.09% id in 178 aa, and to Deinococcus radiodurans putative acetyltransferase DR1800 TR:Q9RTG4 (EMBL:AE002021) (179 aa) fasta scores: E(): 8.9e-08, 29.76% id in 168 aa. (175 aa)    
Predicted Functional Partners:
DIP1859
DeaD/DeaH family helicase; Similar to Escherichia coli probable ATP-dependent helicase DinG SW:DING_ECOLI (P27296) (716 aa) fasta scores: E(): 5.6e-15, 27.57% id in 689 aa, and to Mycobacterium tuberculosis probable ATP-dependent helicase DinG homologue Rv1329c SW:DING_MYCTU (Q10640) (664 aa) fasta scores: E(): 2.2e-131, 55.84% id in 659 aa.
       0.782
DIP1858
Conserved hypothetical protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
  
    0.627
DIP1861
Hypothetical protein; No significant database matches to the full length CDS. C-terminus is similar to an internal region of Mycobacterium tuberculosis hypothetical protein Rv2100 SW:YL00_MYCTU (Q10709) (550 aa) fasta scores: E(): 9.8e-09, 35.15% id in 128 aa.
       0.539
clpS
Conserved hypothetical protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.
       0.471
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
   
    0.463
DIP1856
Similar to Mycobacterium tuberculosis hypothetical protein Rv1332 SW:YD32_MYCTU (Q10643) (218 aa) fasta scores: E(): 1.3e-10, 35.53% id in 197 aa, and to Mycobacterium leprae hypothetical protein ML1166 SW:YD32_MYCLE (P53424) (217 aa) fasta scores: E(): 2.1e-08, 33.5% id in 200 aa. CDS is contains fewer residues at the N-terminus in comparison to the Mycobacterium proteins.
       0.454
DIP1854
Putative membrane protein; Similar to Synechocystis sp. hypothetical protein SLR1461 TR:P74553 (EMBL:D90916) (198 aa) fasta scores: E(): 3e-21, 38.95% id in 172 aa, and to Bacillus halodurans hypothetical protein BH0517 TR:Q9KFG2 (EMBL:AP001508) (248 aa) fasta scores: E(): 3.1e-05, 29.1% id in 189 aa.
  
    0.443
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
  
    0.439
DIP1850
Ham1 family protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
       0.436
DIP1852
Similar to Mycobacterium tuberculosis hypothetical protein Rv1339 SW:YD39_MYCTU (Q10648) (273 aa) fasta scores: E(): 5.5e-46, 46.18% id in 249 aa, and to Mycobacterium leprae hypothetical protein ML1173 SW:YD39_MYCLE (P50474) (284 aa) fasta scores: E(): 6.6e-46, 46.18% id in 249 aa.
       0.434
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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