STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1862Conserved hypothetical protein; Poor database matches. Similar to Streptomyces coelicolor hypothetical protein SC1B5.06c TR:O69834 (EMBL:AL023517) (249 aa) fasta scores: E(): 9e-23, 41.42% id in 210 aa. C-terminal region is similar to Pyrococcus horikoshii hypothetical protein PH1539 SW:YF39_PYRHO (O74017) (121 aa) fasta scores: E(): 0.0025, 36.84% id in 95 aa. (235 aa)    
Predicted Functional Partners:
DIP1863
Putative hydrolase; Similar to Mycobacterium tuberculosis hypothetical protein Rv3042c TR:AAK47457 (EMBL:AL021287) (409 aa) fasta scores: E(): 3.1e-69, 54.54% id in 407 aa, and to Mycobacterium leprae putative phosphoserine phosphatase ML1727 TR:Q9CBQ6 (EMBL:AL583923) (411 aa) fasta scores: E(): 6.2e-66, 53.82% id in 405 aa.
 
     0.864
pth-2
Putative peptidyl tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
      
 0.862
pth
Putative peptidyl tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
      
 0.861
DIP1391
Putative membrane protein; No significant database matches.
      
 0.861
DIP2264
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 123.1 kDa protein Rv1251c or MT1290 or MTV006.23c SWALL:O50466 (EMBL:AL021006) (1139 aa) fasta scores: E(): 1.6, 26.47% id in 544 aa.
  
     0.714
bioD1
Dethiobiotin synthetase; Similar to Corynebacterium glutamicum dethiobiotin synthetase BioD SWALL:BIOD_CORGL (SWALL:P46397) (224 aa) fasta scores: E(): 4e-08, 38.94% id in 208 aa, and to Streptomyces coelicolor dethiobiotin synthetase BioD SWALL:Q9FCC1 (EMBL:AL391014) (238 aa) fasta scores: E(): 3.6e-06, 28.37% id in 222 aa. Note: Similar to the downstream CDS DIP1192, 222 aa; E(): 1.3e-13; 38.914% identity in 221 aa overlap - possible duplication.
  
     0.691
ctaD
Cytochrome C oxidase polypeptide I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B (By similarity).
       0.650
DIP1003
Similar to Streptomyces coelicolor ABC transporter protein, ATP-binding component SCC57A.34c TR:Q9RDG5 (EMBL:AL136519) (1243 aa) fasta scores: E(): 3e-116, 42.18% id in 1247 aa.
  
 
   0.635
DIP1995
Putative membrane protein; Weakly similar to the N-terminal regions of Mycobacterium leprae putative membrane protein ML0228 TR:O69526 (EMBL:AL023093) (432 aa) fasta scores: E(): 0.025, 25.15% id in 318 aa, and to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT3709 TR:AAK48067 (EMBL:AE007170) (397 aa) fasta scores: E(): 0.071, 23.51% id in 336 aa.
  
     0.631
DIP1842
Putative membrane protein; Poor database matches. Similar to Mycobacterium tuberculosis hypothetical protein Rv2520c TR:O53225 (EMBL:AL021185) (75 aa) fasta scores: E(): 2.7e-06, 45.33% id in 75 aa.
  
     0.614
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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