STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1869Conserved hypothetical protein; Similar to Escherichia coli glutaredoxin-like protein NrdH SW:NRDH_ECOLI (Q47414) (81 aa) fasta scores: E(): 4.5e-09, 41.66% id in 72 aa, and to Corynebacterium ammoniagenes NrdH-redoxin TR:O69271 (EMBL:Y09572) (75 aa) fasta scores: E(): 4.4e-23, 81.08% id in 74 aa. (77 aa)    
Predicted Functional Partners:
nrdE
Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 
 0.985
nrdF1
Ribonucleotide reductase beta-chain 1; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.
 
  
 0.972
nrdI-2
Conserved hypothetical protein; Probably involved in ribonucleotide reductase function.
 
  
 0.967
nrdI
Conserved hypothetical protein; Probably involved in ribonucleotide reductase function.
 
  
 0.939
nrdF2
Similar to Escherichia coli ribonucleoside-diphosphate reductase 2 beta chain NrdF SW:RIR4_ECOLI (P37146) (319 aa) fasta scores: E(): 5.4e-72, 56.74% id in 319 aa, and to Mycobacterium leprae ribonucleoside-diphosphate reductase beta chain ML1731 SW:RIR2_MYCLE (Q9CBQ2) (325 aa) fasta scores: E(): 1.5e-74, 61.12% id in 319 aa. Note: Also similar to DIP1865 (328 aa) fasta scores: E(): 5.7e-71, 54.799% identity in 323 aa overlap.
 
  
 0.855
mshD
Putative acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
   
  
 0.616
mshB
Conserved hypothetical protein; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.
      
 0.614
msrA
Peptide methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
 
 0.612
trxB
Thioredoxin reductase; Similar to Mycobacterium smegmatis thioredoxin reductase TrxB SW:TRXB_MYCSM (O30973) (311 aa) fasta scores: E(): 3.1e-72, 64.82% id in 307 aa.
   
 
 0.542
DIP1631
Conserved hypothetical protein; Similar to Corynebacterium glutamicum ORF1 TR:Q9LCB6 (EMBL:AB029550) (114 aa) fasta scores: E(): 3.2e-36, 84.21% id in 114 aa, and to Escherichia coli hypothetical protein YadR or B0156 or Z0167 or ECS0160 SW:YADR_ECOLI (P37026) (114 aa) fasta scores: E(): 7.2e-15, 44.66% id in 103 aa; Belongs to the HesB/IscA family.
  
  
 0.492
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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