STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1870Putative phytoene synthase; Similar to Agrobacterium aurantiacum phytoene synthase CrtB SW:CRTB_AGRAU (P54975) (301 aa) fasta scores: E(): 6.8e-09, 29.57% id in 284 aa, and to Corynebacterium glutamicum phytoene synthase CrtB TR:AAK64298 (EMBL:AF159510) (304 aa) fasta scores: E(): 1.1e-51, 51.22% id in 285 aa. (290 aa)    
Predicted Functional Partners:
DIP1871
Similar to Neurospora crassa phytoene dehydrogenase Al-1 SW:CRTI_NEUCR (P21334) (595 aa) fasta scores: E(): 1.6e-33, 29.77% id in 524 aa, and to Corynebacterium glutamicum phytoene desaturase CrtI TR:AAK64299 (EMBL:AF159510) (549 aa) fasta scores: E(): 5.6e-107, 54.59% id in 511 aa.
  
 0.998
idi
Isopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
 
  
 0.844
DIP1612
Similar to Mycobacterium aurum geranylgeranyl pyrophosphate synthase GgpP TR:Q9K567 (EMBL:AJ133724) (371 aa) fasta scores: E(): 1.5e-36, 39.09% id in 353 aa, and to Sulfolobus acidocaldarius geranylgeranyl pyrophosphate synthetase Gds SW:GGPP_SULAC (P39464) (330 aa) fasta scores: E(): 3.1e-11, 28.49% id in 358 aa.
 
 
 0.785
DIP1474
Putative DNA-damage inducible protein; Similar to Mycobacterium tuberculosis hypothetical 44.8 kDa protein DinF or Rv2836c or MTCY16B7.06 TR:P71616 (EMBL:Z81331) (439 aa) fasta scores: E(): 1e-72, 50.59% id in 423 aa, and to Rhizobium loti DNA-damage-inducible protein MLR5680 TR:Q98B90 (EMBL:AP003007) (471 aa) fasta scores: E(): 1.9e-19, 30.07% id in 429 aa.
   
  
 0.749
DIP0892
Similar to Streptomyces coelicolor putative glyceraldehyde-3-phosphate dehydrogenase SC4G1.06c TR:Q9FC43 (EMBL:AL391039) (481 aa) fasta scores: E(): 1.8e-99, 54.44% id in 472 aa and C-terminal region similar to Bacillus subtilis glyceraldehyde 3-phosphate dehydrogenase 1 GapA or Gap SW:G3P1_BACSU (P09124) (334 aa) fasta scores: E(): 6.7e-40, 41.39% id in 343 aa.
   
  
 0.747
gap
Similar to Corynebacterium glutamicum glyceraldehyde 3-phosphate dehydrogenase Gap SWALL:G3P_CORGL (SWALL:Q01651) (336 aa) fasta scores: E(): 5.5e-99, 80% id in 330 aa, and to Streptomyces coelicolor glyceraldehyde 3-phosphate dehydrogenase Gap or SCC54.07c SWALL:G3P_STRCO (SWALL:Q9Z518) (336 aa) fasta scores: E(): 1.1e-84, 67.26% id in 336 aa; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
   
  
 0.747
rpsA
30S ribosomal protein S1; Similar to Corynebacterium ammoniagenes 30s ribosomal protein S1 RpsA SWALL:Q9LBD0 (EMBL:AF045481) (489 aa) fasta scores: E(): 6e-160, 92.18% id in 486 aa, and to Escherichia coli 30S ribosomal protein S1 RpsA or SsyF or B0911 or Z1257 or ECS0994 SWALL:RS1_ECOLI (SWALL:P02349) (557 aa) fasta scores: E(): 2.9e-52, 44.97% id in 358 aa.
   
    0.744
DIP1315
Putative membrane protein; Similar to Corynebacterium ammoniagenes RibX protein SWALL:O24754 (EMBL:AB003693) (184 aa) fasta scores: E(): 1.3e-34, 45.98% id in 187 aa, and to Mycobacterium leprae putative membrane protein ML0561 SWALL:Q9CCP2 (EMBL:AL583918) (156 aa) fasta scores: E(): 2.3e-15, 37.58% id in 141 aa.
  
 
 0.742
DIP0429
Similar to Mycobacterium leprae polyprenyl diphosphate synthase component ML2277 TR:Q9CBA5 (EMBL:AL583925) (330 aa) fasta scores: E(): 1.6e-57, 51.69% id in 325 aa, and to Bacillus stearothermophilus heptaprenyl diphosphate synthase component II HepT or HepS-2 SW:HEP2_BACST (P55785) (320 aa) fasta scores: E(): 9.6e-33, 38.99% id in 318 aa.
  
 
 0.620
DIP0113
Putative riboflavin biosynthesis protein; Similar to Streptomyces griseus deoxyribodipyrimidine photolyase Phr SW:PHR_STRGR (P12768) (455 aa) fasta scores: E(): 3.5e-36, 36.75% id in 468 aa, and to Escherichia coli deoxyribodipyrimidine photolyase PhrB or Phr or B0708 SW:PHR_ECOLI (P00914) (472 aa) fasta scores: E(): 9.9e-32, 34.01% id in 488 aa; Belongs to the DNA photolyase family.
 
   
 0.566
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.