STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1874Similar to Streptomyces coelicolor hypothetical protein SCJ12.09c TR:Q9RI49 (EMBL:AL109989) (146 aa) fasta scores: E(): 7.2e-10, 38.68% id in 137 aa. C-terminal region is similar to Mycobacterium tuberculosis hypothetical protein Rv3129 TR:O05803 (EMBL:Z95150) (110 aa) fasta scores: E(): 5.1e-11, 47.77% id in 90 aa. (145 aa)    
Predicted Functional Partners:
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
   
    0.769
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
   
    0.745
DIP1417
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT2787 TR:AAK47103 (EMBL:AE007107) (324 aa) fasta scores: E(): 2.1e-45, 45.09% id in 306 aa, and to Streptomyces coelicolor conserved hypothetical protein SCI52.04 TR:Q9ADA5 (EMBL:AL590507) (333 aa) fasta scores: E(): 4.2e-12, 26.64% id in 304 aa.
  
    0.736
DIP0427
Similar to Clostridium acetobutylicum lactate dehydrogenase CAC3552 TR:AAK81477 (EMBL:AE007851) (320 aa) fasta scores: E(): 1.6e-36, 38.6% id in 316 aa, and to Bacillus subtilis L-lactate dehydrogenase Ldh or LctE SW:LDH_BACSU (P13714) (320 aa) fasta scores: E(): 2.9e-25, 33.95% id in 324 aa; Belongs to the LDH/MDH superfamily.
   
    0.648
DIP1875
Hypothetical protein; Poor database matches. C-terminal region is similar to Clostridium acetobutylicum hypothetical protein CAC0072 TR:AAK78058 (EMBL:AE007520) (77 aa) fasta scores: E(): 0.01, 29.16% id in 72 aa.
       0.628
DIP1876
Putative multicopper oxidase; C-terminus is similar to an internal regions of Neisseria gonorrhoeae major anaerobically induced outer membrane protein Pan 1 AniA SW:ANIA_NEIGO (Q02219) (392 aa) fasta scores: E(): 3.5e-18, 30.1% id in 299 aa, and Neisseria meningitidis nitrite reductase, major outer membrane copper-containing protein NMA1887 TR:Q9JTB8 (EMBL:AL162757) (386 aa) fasta scores: E(): 3e-18, 30.43% id in 299 aa.
       0.628
DIP1877
Putative membrane protein; No significant database matches to the full length CDS. C-terminus is similar to the N-terminal regions of Rhizobium meliloti hypothetical protein SMA0447 TR:AAK64892 (EMBL:AE007216) (373 aa) fasta scores: E(): 0.48, 22.94% id in 353 aa.
       0.628
DIP1878
Putative membrane protein; Poor database matches. C-terminal region is weakly similar to Sulfolobus solfataricus hypothetical protein Sso2014 sso2014 TR:Q97WV0 (EMBL:AE006808) (307 aa) fasta scores: E(): 0.44, 21.34% id in 328 aa.
       0.628
DIP1879
Putative DNA-biding protein; Similar to Mycobacterium tuberculosis hypothetical protein Rv2621c TR:O06191 (EMBL:Z95387) (224 aa) fasta scores: E(): 2.3e-05, 27.12% id in 188 aa, and to Deinococcus radiodurans conserved hypothetical protein DR0999 TR:Q9RvM8 (EMBL:AE001952) (225 aa) fasta scores: E(): 0.01, 23.62% id in 182 aa.
 
     0.572
DIP0955
Hypothetical protein; No significant database matches.
  
     0.547
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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