Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DIP1877Putative membrane protein; No significant database matches to the full length CDS. C-terminus is similar to the N-terminal regions of Rhizobium meliloti hypothetical protein SMA0447 TR:AAK64892 (EMBL:AE007216) (373 aa) fasta scores: E(): 0.48, 22.94% id in 353 aa. (430 aa)    
Predicted Functional Partners:
DIP1876
Putative multicopper oxidase; C-terminus is similar to an internal regions of Neisseria gonorrhoeae major anaerobically induced outer membrane protein Pan 1 AniA SW:ANIA_NEIGO (Q02219) (392 aa) fasta scores: E(): 3.5e-18, 30.1% id in 299 aa, and Neisseria meningitidis nitrite reductase, major outer membrane copper-containing protein NMA1887 TR:Q9JTB8 (EMBL:AL162757) (386 aa) fasta scores: E(): 3e-18, 30.43% id in 299 aa.
     0.994
DIP1875
Hypothetical protein; Poor database matches. C-terminal region is similar to Clostridium acetobutylicum hypothetical protein CAC0072 TR:AAK78058 (EMBL:AE007520) (77 aa) fasta scores: E(): 0.01, 29.16% id in 72 aa.
 
     0.947
DIP1878
Putative membrane protein; Poor database matches. C-terminal region is weakly similar to Sulfolobus solfataricus hypothetical protein Sso2014 sso2014 TR:Q97WV0 (EMBL:AE006808) (307 aa) fasta scores: E(): 0.44, 21.34% id in 328 aa.
 
     0.947
DIP1879
Putative DNA-biding protein; Similar to Mycobacterium tuberculosis hypothetical protein Rv2621c TR:O06191 (EMBL:Z95387) (224 aa) fasta scores: E(): 2.3e-05, 27.12% id in 188 aa, and to Deinococcus radiodurans conserved hypothetical protein DR0999 TR:Q9RvM8 (EMBL:AE001952) (225 aa) fasta scores: E(): 0.01, 23.62% id in 182 aa.
 
     0.882
DIP0494
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 hypothetical 24.2 kDa protein MT2696 TR:AAK47012 (EMBL:AE007102) (224 aa) fasta scores: E(): 1.3e-10, 31.37% id in 204 aa.
 
     0.766
DIP0066
Putative exported protein; No database matches.
 
  
 0.703
DIP1874
Similar to Streptomyces coelicolor hypothetical protein SCJ12.09c TR:Q9RI49 (EMBL:AL109989) (146 aa) fasta scores: E(): 7.2e-10, 38.68% id in 137 aa. C-terminal region is similar to Mycobacterium tuberculosis hypothetical protein Rv3129 TR:O05803 (EMBL:Z95150) (110 aa) fasta scores: E(): 5.1e-11, 47.77% id in 90 aa.
       0.628
DIP1216
Conserved hypothetical protein; Low similarity to Agrobacterium tumefaciens StrC58 AGR_C_2998p SWALL:AAK87404 (EMBL:AE008084) (321 aa) fasta scores: E(): 2.8e-06, 31.33% id in 150 aa, and to Rhizobium meliloti hypothetical protein RB0059 or SMB20059 SWALL:CAC48459 (EMBL:AL603642) (259 aa) fasta scores: E(): 6.5e-05, 28.67% id in 143 aa.
  
     0.530
qcrC
Ubiquinol-cytochrome C reductase cytochrome C subunit; Cytochrome c1 subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
  
  
 0.475
DIP2170
Conserved hypothetical integral membrane protein; Similar to Bacillus subtilis hypothetical 27.6 kDa protein in fnr-narG intergenic region YwiC SW:YWIC_BACSU (P46909) (239 aa) fasta scores: E(): 5e-08, 28.571% id in 259 aa, and to Haemophilus influenzae hypothetical protein HI1626 SW:YG26_HAEIN (P44278) (238 aa) fasta scores: E(): 3.6e-06, 25.758% id in 264 aa.
  
     0.457
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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