STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1880Putative exported protein; Poor database matches. Weakly similar to Streptomyces coelicolor hypothetical protein SC4G6.36 TR:Q9S2S3 (EMBL:AL096884) (266 aa) fasta scores: E(): 4.7e-06, 26.22% id in 225 aa, and to Mycobacterium leprae possible conserved membrane protein ML1667 TR:Q9CBS4 (EMBL:AL583923) (264 aa) fasta scores: E(): 1.5e-05, 28.77% id in 212 aa. (244 aa)    
Predicted Functional Partners:
DIP0411
Putative electron transport related protein; Similar to Deinococcus radiodurans thiol:disulfide interchange protein DR0189 TR:Q9RXW6 (EMBL:AE001881) (185 aa) fasta scores: E(): 7.1e-09, 34.84% id in 132 aa, and to Bacillus halodurans thioredoxin BH1522 TR:Q9KCP7 (EMBL:AP001512) (177 aa) fasta scores: E(): 3.4e-08, 34.12% id in 126 aa and to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT0548 TR:AAK44771 (EMBL:AE006954) (216 aa) fasta scores: E(): 9.2e-31, 48.95% id in 192 aa.
  
 
 0.768
DIP1881
Putative membrane protein; Poor database matches. Similar to the N-terminal regions of Paracoccus denitrificans methylamine utilization protein MauE SW:MAUE_PARDE (P29896) (186 aa) fasta scores: E(): 0.00023, 30.89% id in 123 aa, and Methylobacterium extorquens methylamine utilization protein MauE SW:MAUE_METEX (Q49125) (187 aa) fasta scores: E(): 0.026, 29% id in 100 aa.
       0.733
crcB2
Putative membrane protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
 
     0.677
pgm
Phosphoglucomutase; Similar to Escherichia coli phosphoglucomutase Pgm SW:PGMU_ECOLI (P36938) (546 aa) fasta scores: E(): 2.7e-133, 62.5% id in 544 aa, and to Mycobacterium tuberculosis hypothetical protein Rv3068c TR:P95090 (EMBL:Z83866) (547 aa) fasta scores: E(): 7e-150, 69.76% id in 549 aa.
       0.671
pknB
Similar to Mycobacterium leprae probable serine/threonine-protein kinase PknB or ML0016 SW:PKNB_MYCLE (P54744) (622 aa) fasta scores: E(): 5.7e-58, 43.26% id in 661 aa.
      
 0.662
crcB1
Putative membrane protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
 
     0.657
DIP0397
Putative secreted protein; Similar to Streptomyces coelicolor putative membrane protein SCBAC16H6.28 TR:CAC44607 (EMBL:AL596162) (270 aa) fasta scores: E(): 4.9e-22, 39.13% id in 207 aa.
      
 0.636
DIP1410
Putative membrane protein; No significant database matches.
 
     0.611
DIP0792
Hypothetical protein; No significant database matches.
  
     0.555
DIP2370
Putative secreted protein; Weak but full length similarity to Mycobacterium tuberculosis hypothetical 83.9 kDa protein Rv3909 or MTCY15F10.02c TR:O05436 (EMBL:Z94121) (802 aa) fasta scores: E(): 8.4e-10, 25.54% id in 916 aa.
  
     0.471
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: low (30%) [HD]