STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1881Putative membrane protein; Poor database matches. Similar to the N-terminal regions of Paracoccus denitrificans methylamine utilization protein MauE SW:MAUE_PARDE (P29896) (186 aa) fasta scores: E(): 0.00023, 30.89% id in 123 aa, and Methylobacterium extorquens methylamine utilization protein MauE SW:MAUE_METEX (Q49125) (187 aa) fasta scores: E(): 0.026, 29% id in 100 aa. (150 aa)    
Predicted Functional Partners:
pgm
Phosphoglucomutase; Similar to Escherichia coli phosphoglucomutase Pgm SW:PGMU_ECOLI (P36938) (546 aa) fasta scores: E(): 2.7e-133, 62.5% id in 544 aa, and to Mycobacterium tuberculosis hypothetical protein Rv3068c TR:P95090 (EMBL:Z83866) (547 aa) fasta scores: E(): 7e-150, 69.76% id in 549 aa.
       0.765
DIP1880
Putative exported protein; Poor database matches. Weakly similar to Streptomyces coelicolor hypothetical protein SC4G6.36 TR:Q9S2S3 (EMBL:AL096884) (266 aa) fasta scores: E(): 4.7e-06, 26.22% id in 225 aa, and to Mycobacterium leprae possible conserved membrane protein ML1667 TR:Q9CBS4 (EMBL:AL583923) (264 aa) fasta scores: E(): 1.5e-05, 28.77% id in 212 aa.
       0.745
crcB1
Putative membrane protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
       0.653
crcB2
Putative membrane protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
       0.653
DIP2179
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 27.5 kDa protein Rv0224c or MTCY08D5.19c TR:P96406 (EMBL:Z92669) (254 aa) fasta scores: E(): 2.9e-56, 63.41% id in 246 aa, and to Streptomyces coelicolor putative methyltransferase SCC53.08c TR:Q9KXK3 (EMBL:AL357591) (244 aa) fasta scores: E(): 7.1e-06, 32.94% id in 173 aa.
  
     0.408
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: medium (56%) [HD]