STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgmPhosphoglucomutase; Similar to Escherichia coli phosphoglucomutase Pgm SW:PGMU_ECOLI (P36938) (546 aa) fasta scores: E(): 2.7e-133, 62.5% id in 544 aa, and to Mycobacterium tuberculosis hypothetical protein Rv3068c TR:P95090 (EMBL:Z83866) (547 aa) fasta scores: E(): 7e-150, 69.76% id in 549 aa. (545 aa)    
Predicted Functional Partners:
pgi
Similar to Escherichia coli glucose-6-phosphate isomerase Pgi or B4025 or Z5623 or ECS5008 SW:G6PI_ECOLI (P11537) (549 aa) fasta scores: E(): 2e-104, 52.71% id in 552 aa, and to Mycobacterium tuberculosis glucose-6-phosphate isomerase Pgi or Rv0946c or MT0972 or MTCY10D7.28 SW:G6PI_MYCTU (P77895) (553 aa) fasta scores: E(): 2.6e-133, 62.75% id in 545 aa.
  
 0.986
DIP1552
Putative glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
  
 
 0.984
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
    
 0.939
glgB
1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
 
  
 0.936
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.931
rbsK
Putative ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
   
 0.929
DIP1726
Putative glucanotransferase; Similar to Mycobacterium tuberculosis 4-alpha-glucanotransferase MalQ or Rv1781c or MT1831 or MTV049.03c SW:MALQ_MYCTU (O53932) (724 aa) fasta scores: E(): 7.8e-73, 45.87% id in 728 aa, and to Escherichia coli 4-alpha-glucanotransferase MalQ or MalA or B3416 SW:MALQ_ECOLI (P15977) (694 aa) fasta scores: E(): 1.2e-29, 28.48% id in 660 aa.
  
 
 0.928
DIP0862
Putative urydyltransferase; Similar to Mycobacterium tuberculosis CDC1551 UTP--glucose-1-phosphate uridylyltransferase MT1022 TR:AAK45269 (EMBL:AE006986) (306 aa) fasta scores: E(): 3.2e-65, 64.8% id in 287 aa, and to Bacillus subtilis UTP--glucose-1-phosphate uridylyltransferase GtaB SW:GTAB_BACSU (Q05852) (292 aa) fasta scores: E(): 1.4e-32, 40.67% id in 295 aa.
    
 0.927
glk
Glucose kinase; Similar to Corynebacterium glutamicum glucose kinase Glk TR:Q9KKE7 (EMBL:AF096280) (323 aa) fasta scores: E(): 2.5e-79, 62.38% id in 319 aa, and to Streptomyces coelicolor glucokinase Glk or SC6E10.20c SW:GLK_STRCO (P40184) (317 aa) fasta scores: E(): 5.7e-45, 40% id in 310 aa.
     
 0.927
DIP0991
Putative glycosyltransferase; Similar to Mycobacterium tuberculosis CDC1551 glycosyl transferase MT1250 TR:AAK45507 (EMBL:AE007001) (387 aa) fasta scores: E(): 2.9e-91, 60.72% id in 387 aa, and to Bacillus subtilis spore coat protein SA CotSA SW:CTSA_BACSU (P46915) (377 aa) fasta scores: E(): 1.6e-13, 24.37% id in 402 aa.
  
 0.925
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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