STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1885Similar to Streptomyces coelicolor putative ABC transport system integral membrane protein SCE41.19c TR:Q9F2P0 (EMBL:AL442120) (854 aa) fasta scores: E(): 6.5e-62, 30.8% id in 870 aa, and to Streptomyces coelicolor putative ABC transporter integral membrane protein SCE25.31 TR:Q9KZ59 (EMBL:AL354048) (843 aa) fasta scores: E(): 2.6e-41, 33.83% id in 857 aa. (854 aa)    
Predicted Functional Partners:
DIP1886
Similar to Streptomyces coelicolor putative ABC transport system ATP-binding protein SCE41.20c TR:Q9F2N9 (EMBL:AL442120) (262 aa) fasta scores: E(): 9.4e-54, 63.9% id in 241 aa, and to Streptomyces coelicolor putative ABC transporter ATP-binding protein SCE25.30 TR:Q9KZ60 (EMBL:AL354048) (256 aa) fasta scores: E(): 4.6e-53, 67.37% id in 236 aa.
 
  
 0.997
DIP0484
Putative ABC transport system ATP-binding protein; Similar to Bacillus subtilis YknY protein TR:O31711 (EMBL:Z99111) (230 aa) fasta scores: E(): 3.2e-43, 57.01% id in 221 aa.
 
  
 0.905
DIP0483
Putative secreted protein; C-terminal region presents los similarity to Streptococcus pneumoniae hypothetical protein SP0785 TR:AAK74922 (EMBL:AE007385) (399 aa) fasta scores: E(): 4e-08, 28.25% id in 315 aa.
  
    0.825
DIP0485
Putative ABC transport system integral membrane protein; Similar to Bacillus halodurans BH3121 protein TR:Q9K885 (EMBL:AP001517) (398 aa) fasta scores: E(): 4e-20, 33.33% id in 438 aa.
 
   
0.804
clpB2
Putative heat shock protein (partial); Similar to Corynebacterium glutamicum ClpB protein SWALL:CLPB_CORGL (SWALL:P53532) (852 aa) fasta scores: E(): 0.027, 44.44% id in 99 aa, and to Mycobacterium leprae heat shock protein ClpB or ML2490 SWALL:Q9CB26 (EMBL:AL583925) (848 aa) fasta scores: E(): 0.66, 35.41% id in 96 aa. Note: Similar also to the C-terminal part of DIP2104 (849 aa) E(): 7.2e-08; 53.465% identity in 101 aa overlap.
   
    0.677
clpB
Putative ATP-dependent protease regulatory subunit, ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity). Belong [...]
   
    0.677
DIP0448
Similar to Streptomyces coelicolor putative ABC transport system ATP-binding protein SCE41.20c TR:Q9F2N9 (EMBL:AL442120) (262 aa) fasta scores: E(): 2.4e-29, 44.49% id in 236 aa.
 
  
 0.474
DIP2049
Low similarity to Streptomyces coelicolor putative ABC transporter integral membrane protein SCE8.16c SWALL:Q9Z4W1 (EMBL:AL035654) (264 aa) fasta scores: E(): 1.7e-09, 26.37% id in 254 aa.
  
     0.440
DIP0504
Putative molybdopterin biosynthesis protein; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.
  
     0.400
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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