STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1886Similar to Streptomyces coelicolor putative ABC transport system ATP-binding protein SCE41.20c TR:Q9F2N9 (EMBL:AL442120) (262 aa) fasta scores: E(): 9.4e-54, 63.9% id in 241 aa, and to Streptomyces coelicolor putative ABC transporter ATP-binding protein SCE25.30 TR:Q9KZ60 (EMBL:AL354048) (256 aa) fasta scores: E(): 4.6e-53, 67.37% id in 236 aa. (249 aa)    
Predicted Functional Partners:
DIP1885
Similar to Streptomyces coelicolor putative ABC transport system integral membrane protein SCE41.19c TR:Q9F2P0 (EMBL:AL442120) (854 aa) fasta scores: E(): 6.5e-62, 30.8% id in 870 aa, and to Streptomyces coelicolor putative ABC transporter integral membrane protein SCE25.31 TR:Q9KZ59 (EMBL:AL354048) (843 aa) fasta scores: E(): 2.6e-41, 33.83% id in 857 aa.
 
  
 0.997
DIP0485
Putative ABC transport system integral membrane protein; Similar to Bacillus halodurans BH3121 protein TR:Q9K885 (EMBL:AP001517) (398 aa) fasta scores: E(): 4e-20, 33.33% id in 438 aa.
 
 0.996
DIP0483
Putative secreted protein; C-terminal region presents los similarity to Streptococcus pneumoniae hypothetical protein SP0785 TR:AAK74922 (EMBL:AE007385) (399 aa) fasta scores: E(): 4e-08, 28.25% id in 315 aa.
  
 
 0.899
DIP0484
Putative ABC transport system ATP-binding protein; Similar to Bacillus subtilis YknY protein TR:O31711 (EMBL:Z99111) (230 aa) fasta scores: E(): 3.2e-43, 57.01% id in 221 aa.
  
   
0.800
DIP1576
Putative RNA-binding heat shock protein; Similar to Rhizobium loti MLR3853 protein TR:Q98FB3 (EMBL:AP003002) (131 aa) fasta scores: E(): 2.9e-09, 42.01% id in 119 aa, and to Escherichia coli heat shock protein 15 HslR or B3400 or Z4754 or ECS4242 SW:HSLR_ECOLI (P45802) (133 aa) fasta scores: E(): 2.7e-06, 32.54% id in 126 aa.
   
    0.744
DIP2324
Similar to Streptomyces coelicolor putative ABC transport system transmembrane protein SC10A9.10c SWALL:Q9AK94 (EMBL:AL583943) (379 aa) fasta scores: E(): 4.3e-17, 38.94% id in 380 aa. Lies alongside a putative ABC transporter ATP-binding subunit.
 
 
 0.719
DIP0449
Putative ABC transport system integral membrane protein; Low similarity to Staphylococcus aureus, ABC transporter VraE or SA2493 or SAV2702 TR:Q9KWJ6 (EMBL:AB035452) (626 aa) fasta scores: E(): 0.066, 21.03% id in 385 aa.
  
 
 0.707
clpB2
Putative heat shock protein (partial); Similar to Corynebacterium glutamicum ClpB protein SWALL:CLPB_CORGL (SWALL:P53532) (852 aa) fasta scores: E(): 0.027, 44.44% id in 99 aa, and to Mycobacterium leprae heat shock protein ClpB or ML2490 SWALL:Q9CB26 (EMBL:AL583925) (848 aa) fasta scores: E(): 0.66, 35.41% id in 96 aa. Note: Similar also to the C-terminal part of DIP2104 (849 aa) E(): 7.2e-08; 53.465% identity in 101 aa overlap.
  
  
 0.687
clpB
Putative ATP-dependent protease regulatory subunit, ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity). Belong [...]
  
  
 0.687
DIP0419
Conserved hypothetical protein; Low similarity in parts to Mycobacterium tuberculosis hypothetical 58.9 kDa protein precursor Rv2100 or MT2160 or MTCY49.40 SW:YL00_MYCTU (Q10709) (550 aa) fasta scores: E(): 1.7e-06, 32.57% id in 132 aa.
  
 
 0.496
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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