Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DIP1894Hypothetical protein; No significant database matches to the full length CDS. Internal region is weakly similar to an internal region of Thermoplasma volcanium hypothetical protein TVG1552703 TR:BAB60643 (EMBL:AP000996) (974 aa) fasta scores: E(): 5.5e-05, 21.86% id in 773 aa. (865 aa)    
Predicted Functional Partners:
DIP1895
Putative DNA methylase; Internal region is similar to an internal regions of Salmonella typhimurium type III restriction-modification system StyLTI enzyme Mod SW:T3MO_SALTY (P40814) (651 aa) fasta scores: E(): 1.8e-20, 29.39% id in 398 aa, and Xylella fastidiosa methyltransferase XF1968 TR:Q9PC17 (EMBL:AE004016) (534 aa) fasta scores: E(): 5.9e-33, 35.25% id in 417 aa.
 
     0.948
DIP0805
Putative DNA methylase; Similar to Haemophilus influenzae putative type III restriction-modification system HinDVIp enzyme Mod HI1056 SW:T3MH_HAEIN (P71366) (629 aa) fasta scores: E(): 8.3e-26, 29.960% id in 504 aa, and to Lactococcus lactis modification methylase LlaFI Mod TR:Q9Z6H7 (EMBL:AF054600) (680 aa) fasta scores: E(): 5.8e-13, 29.369% id in 412 aa.
 
     0.783
DIP2208
Similar to Escherichia coli hypothetical protein YgcI precursor or B2757 SW:YGCI_ECOLI (Q46898) (224 aa) fasta scores: E(): 0.02, 26.816% id in 179 aa.
  
     0.662
DIP2212
Similar to Escherichia coli hypothetical 22.3 kDa protein in iap-cysH intergenic region YgcH or B2756 SW:YGCH_ECOLI (Q46897) (199 aa) fasta scores: E(): 0.042, 24.873% id in 197 aa.
  
     0.657
DIP2213
Putative helicase; Similar to Escherichia coli hypothetical 100.5 kDa protein in iap-cysH intergenic region YgcB or B2761 SW:YGCB_ECOLI (P38036) (888 aa) fasta scores: E(): 1.1e-28, 28.827% id in 784 aa.
  
     0.600
DIP1859
DeaD/DeaH family helicase; Similar to Escherichia coli probable ATP-dependent helicase DinG SW:DING_ECOLI (P27296) (716 aa) fasta scores: E(): 5.6e-15, 27.57% id in 689 aa, and to Mycobacterium tuberculosis probable ATP-dependent helicase DinG homologue Rv1329c SW:DING_MYCTU (Q10640) (664 aa) fasta scores: E(): 2.2e-131, 55.84% id in 659 aa.
   
 0.551
rpoB
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
  0.516
rpoA
DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.509
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.508
DIP2209
Conserved hypothetical protein; Similar to Escherichia coli O157:H7 hypothetical 38.4 kDa protein ECS3612 TR:BAB37035 (EMBL:AP002562) (351 aa) fasta scores: E(): 8.7e-11, 33.333% id in 306 aa.
  
     0.497
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.