STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1898Putative cytochrome ubiquinol oxidase subunit; N-terminus is similar to the N-terminal region of Escherichia coli cytochrome D ubiquinol oxidase subunit I CydA SW:CYDA_ECOLI (P11026) (522 aa) fasta scores: E(): 5.2e-47, 37.11% id in 485 aa. Similar to Mycobacterium tuberculosis probable cytochrome D ubiquinol oxidase subunit Rv1623c TR:O06140 (EMBL:Z95554) (485 aa) fasta scores: E(): 4.5e-121, 62.11% id in 483 aa. (503 aa)    
Predicted Functional Partners:
DIP1899
Similar to Escherichia coli cytochrome D ubiquinol oxidase subunit II CydB SW:CYDB_ECOLI (P11027) (379 aa) fasta scores: E(): 9.8e-28, 37.63% id in 364 aa, and to Corynebacterium glutamicum cytochrome BD-type menaquinol oxidase subunit II CydB TR:Q9KWL7 (EMBL:AB035086) (334 aa) fasta scores: E(): 3.4e-63, 54.26% id in 328 aa.
 
 0.999
DIP1900
Similar to Bacillus subtilis transport ATP-binding protein CydC SW:CYDC_BACSU (P94366) (567 aa) fasta scores: E(): 2.3e-21, 31.8% id in 544 aa, and to Vibrio cholerae transport ATP-binding protein VC1181 TR:Q9KSS5 (EMBL:AE004198) (595 aa) fasta scores: E(): 2.5e-19, 27.76% id in 551 aa. CDS is extended at the N-terminus in comparison to similar proteins. Possible alternative translational start site.
 
  
 0.998
DIP1901
Putative ABC transport system ATP-binding protein; Similar to Mycobacterium tuberculosis Rv1620c TR:O06137 (EMBL:Z95554) (576 aa) fasta scores: E(): 2.2e-20, 38.71% id in 527 aa, and to Caulobacter crescentus ABC transporter, ATP-binding protein CC0761 TR:Q9AA45 (EMBL:AE005752) (546 aa) fasta scores: E(): 5.8e-16, 28.73% id in 529 aa.
 
  
 0.997
DIP0014
Putative membrane protein; Low similarity to Staphylococcus aureus subsp aureus N315 SA0639 protein TR:Q99VT7 (EMBL:AP003131) (543 aa) fasta scores: E(): 3e-23, 25.56% id in 485 aa.
 
  
 0.832
DIP0371
Similar to Bacillus subtilis succinate dehydrogenase flavoprotein subunit SdhA or CitF SWALL:DHSA_BACSU (SWALL:P08065) (585 aa) fasta scores: E(): 5.8e-26, 34.71% id in 579 aa, and to Escherichia coli fumarate reductase flavoprotein subunit FrdA or B4154 SWALL:FRDA_ECOLI (SWALL:P00363) (601 aa) fasta scores: E(): 5.7e-18, 31.72% id in 580 aa.
     
 0.729
qcrC
Ubiquinol-cytochrome C reductase cytochrome C subunit; Cytochrome c1 subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
  
  
 0.661
DIP0372
Similar to Bacillus subtilis succinate dehydrogenase iron-sulfur protein SdhB SWALL:DHSB_BACSU (SWALL:P08066) (252 aa) fasta scores: E(): 1.3e-08, 27.45% id in 255 aa, and to Escherichia coli succinate dehydrogenase iron-sulfur protein SdhB or B0724 SWALL:DHSB_ECOLI (SWALL:P07014) (238 aa) fasta scores: E(): 6.8e-08, 29.43% id in 248 aa.
     
 0.609
DIP1357
Hypothetical protein; No significant database matches.
  
  
 0.534
qcrB
Ubiquinol-cytochrome C reductase cytochrome B subunit; Cytochrome b subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
     
 0.531
DIP0370
Low similarity to Bacillus pseudofirmus succinate dehydrogenease cytochrome B-558 subunit DhsC SWALL:O54447 (EMBL:U91843) (159 aa) fasta scores: E(): 0.011, 28.22% id in 163 aa, and to Streptomyces coelicolor putative cytochrome B subunit SCM10.12c TR:Q9RCY6 (EMBL:AL133469) (243 aa) fasta scores: E(): 1.8e-18, 36.01% id in 236 aa.
     
  0.499
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.