Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cat1Similar to Clostridium kluyveri succinyl-CoA:coenzyme A transferase Cat1 SWALL:CAT1_CLOKL (SWALL:P38946) (538 aa) fasta scores: E(): 1.8e-85, 47.56% id in 513 aa, and to Caulobacter crescentus coenzyme A transferase, putative CC3724 SWALL:Q9A242 (EMBL:AE006030) (514 aa) fasta scores: E(): 1.3e-97, 52.96% id in 506 aa. (517 aa)    
Predicted Functional Partners:
sbm
Putative methylmalonyl-CoA mutase large subunit; Similar to Escherichia coli Sbm protein or B2917 SWALL:SBM_ECOLI (SWALL:P27253) (714 aa) fasta scores: E(): 1.6e-148, 60.2% id in 696 aa, and to Mycobacterium tuberculosis probable methylmalonyl-CoA mutase large subunit MutB or Rv1493 or MT1540 or MTCY277.15 SWALL:MUTB_MYCTU (SWALL:P71774) (750 aa) fasta scores: E(): 4.8e-198, 76.55% id in 708 aa.
  
 
 0.954
odhA
2-oxoglutarate dehydrogenase, E1 and E2 components; Similar to Corynebacterium glutamicum 2-oxoglutarate dehydrogenase OdhA TR:P96746 (EMBL:D84102) (1257 aa) fasta scores: E(): 0, 77.37% id in 1242 aa, and to Mycobacterium leprae 2-oxoglutarate dehydrogenase, E1 and E2 components OdhA or ML1095 TR:Q9CC97 (EMBL:AL583920) (1260 aa) fasta scores: E(): 0, 59.37% id in 1253 aa. Similar in the N-terminus to Escherichia coli dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex (E2) SucB or B0727 or Z0881 or ECS0752 SW:ODO2_ECOLI (P07016) blastp scores: E(): 4 [...]
   
 0.942
DIP2115
Putative aldehyde dehydrogenase; Similar to many eg. Acinetobacter spM-1. aldehyde dehydrogenase 1 Ald1 TR:Q9FDS1 (EMBL:AB042203) (503 aa) fasta scores: E(): 2.5e-143, 69.18% id in 503 aa, and to Alcaligenes eutrophus acetaldehyde dehydrogenase II AcoD SW:DHA2_ALCEU (P46368) (506 aa) fasta scores: E(): 1.8e-135, 66.39% id in 497 aa.
  
 
 0.925
DIP2331
Putative aldehyde dehydrogenase; Similar to Deinococcus radiodurans succinate-semialdehyde dehydrogenase [NADP+] SsdA or DRA0343 SWALL:GABD_DEIRA (SWALL:O32507) (477 aa) fasta scores: E(): 1.2e-81, 49.44% id in 453 aa, and to Streptomyces coelicolor putative aldehyde dehydrogenase 2SCG58.04 SWALL:Q9FCA9 (EMBL:AL391017) (461 aa) fasta scores: E(): 4.1e-65, 42.57% id in 458 aa, and to Ustilago maydis indole-3-acetaldehyde dehydrogenase Iad1 SWALL:Q92460 (EMBL:U74468) (497 aa) fasta scores: E(): 1.6e-48, 37.04% id in 467 aa.
  
 
 0.925
pta
Phosphate acetyltransferase; Highly similar in its C-terminal region to Corynebacterium glutamicum phosphate acetyltransferase Pta SWALL:PTA_CORGL (SWALL:P77844) (329 aa) fasta scores: E(): 6.9e-94, 78.22% id in 326 aa, similar to the C-terminal region of Mycobacterium tuberculosis phosphate acetyltransferase Pta or Rv0408 or MT0421 or MTCY22G10.04 SWALL:PTA_MYCTU (SWALL:P96254) (690 aa) fasta scores: E(): 4.8e-68, 48.67% id in 452 aa, and similar to the C-terminal region of Escherichia coli phosphate acetyltransferase Pta or B2297 SWALL:PTA_ECOLI (SWALL:P39184) (713 aa) fasta scores: [...]
    
 0.924
DIP0833
Similar to Escherichia coli succinate-semialdehyde dehydrogenase [NADP+] GabD or B2661 SW:GABD_ECOLI (P25526) (482 aa) fasta scores: E(): 2.9e-76, 44.37% id in 471 aa.
  
 
 0.923
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
     
 0.922
pdhC
Similar to Acholeplasma laidlawii dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex PdhC SW:ODP2_ACHLA (P35489) (544 aa) fasta scores: E(): 8.7e-49, 37.7% id in 541 aa, to Mycobacterium tuberculosis dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex SucB or Rv2215 or MT2272 or MTCY190.26 SW:ODO2_MYCTU (Q10381) (553 aa) fasta scores: E(): 8.9e-95, 58.49% id in 559 aa, and to Bacillus stearothermophilus dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex PdhC SW:ODP2_BACST (P11961) (427 aa) fasta [...]
   
 0.915
DIP0372
Similar to Bacillus subtilis succinate dehydrogenase iron-sulfur protein SdhB SWALL:DHSB_BACSU (SWALL:P08066) (252 aa) fasta scores: E(): 1.3e-08, 27.45% id in 255 aa, and to Escherichia coli succinate dehydrogenase iron-sulfur protein SdhB or B0724 SWALL:DHSB_ECOLI (SWALL:P07014) (238 aa) fasta scores: E(): 6.8e-08, 29.43% id in 248 aa.
   
 
 0.914
accBC
Similar to Corynebacterium glutamicum acyl coenzyme A carboxylase AccBC TR:P71122 (EMBL:U35023) (591 aa) fasta scores: E(): 1.5e-188, 85.47% id in 592 aa, and to Mycobacterium leprae acetyl-/propionyl-coenzyme A carboxylase alpha chain [includes: biotin carboxylase (EC 6.3.4.14); biotin carboxyl carrier protein(BCCP)] BccA or ML0726 or B1308_C1_129 SW:BCCA_MYCLE (P46392) (598 aa) fasta scores: E(): 1.1e-159, 72.46% id in 592 aa.
    
 0.909
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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