Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
DIP1904Conserved hypothetical protein; Similar to Mycobacterium tuberculosis phosphate transport system protein PhoU homolog 2 Rv0821c SW:PHU2_MYCTU (O53833) (213 aa) fasta scores: E(): 2.1e-32, 42.72% id in 213 aa, and to Mycobacterium leprae phosphate transport system protein PhoU homolog 1 ML2188 SW:PHU1_MYCLE (Q50047) (222 aa) fasta scores: E(): 8.5e-31, 40.93% id in 215 aa. (250 aa)    
Predicted Functional Partners:
pstA
Putative phosphate transport ATP-binding protein (pseudogene); ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop).
 
  
 0.971
pstC
Phosphate transport system permease protein; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
  
 0.880
DIP1910
Putative phosphate-binding periplasmic protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.
 
  
 0.835
DIP1903
Putative exported protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
       0.799
DIP0390
Putative two component system sensor kinase; Similar to Mycobacterium tuberculosis sensor-like histidine kinase SenX3 or Rv0490 or MT0509 or MTCY20G9.16 SW:SEX3_MYCTU (Q11155) (410 aa) fasta scores: E(): 3.6e-60, 48.84% id in 389 aa.
 
   
 0.638
cat1
Similar to Clostridium kluyveri succinyl-CoA:coenzyme A transferase Cat1 SWALL:CAT1_CLOKL (SWALL:P38946) (538 aa) fasta scores: E(): 1.8e-85, 47.56% id in 513 aa, and to Caulobacter crescentus coenzyme A transferase, putative CC3724 SWALL:Q9A242 (EMBL:AE006030) (514 aa) fasta scores: E(): 1.3e-97, 52.96% id in 506 aa.
     
 0.575
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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