STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nrdIConserved hypothetical protein; Probably involved in ribonucleotide reductase function. (141 aa)    
Predicted Functional Partners:
nrdF2
Similar to Escherichia coli ribonucleoside-diphosphate reductase 2 beta chain NrdF SW:RIR4_ECOLI (P37146) (319 aa) fasta scores: E(): 5.4e-72, 56.74% id in 319 aa, and to Mycobacterium leprae ribonucleoside-diphosphate reductase beta chain ML1731 SW:RIR2_MYCLE (Q9CBQ2) (325 aa) fasta scores: E(): 1.5e-74, 61.12% id in 319 aa. Note: Also similar to DIP1865 (328 aa) fasta scores: E(): 5.7e-71, 54.799% identity in 323 aa overlap.
 
 
 0.990
nrdE
Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 
  
 0.984
nrdF1
Ribonucleotide reductase beta-chain 1; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.
 
 
 0.972
DIP1869
Conserved hypothetical protein; Similar to Escherichia coli glutaredoxin-like protein NrdH SW:NRDH_ECOLI (Q47414) (81 aa) fasta scores: E(): 4.5e-09, 41.66% id in 72 aa, and to Corynebacterium ammoniagenes NrdH-redoxin TR:O69271 (EMBL:Y09572) (75 aa) fasta scores: E(): 4.4e-23, 81.08% id in 74 aa.
 
  
 0.939
slpA
Surface layer protein A; Similar to Corynebacterium ammoniagenes surface layer protein A SlpA TR:BAB62413 (EMBL:AB055224) (358 aa) fasta scores: E(): 1.4e-69, 52.76% id in 362 aa, and to Mycobacterium tuberculosis antigen 85-A precursor FbpA or MPT44 or Rv3804c or MT3911 or MTV026.09c SW:A85A_MYCTU (P17944) (338 aa) fasta scores: E(): 9.7e-18, 31.56% id in 320 aa.
      
 0.585
DIP1922
Putative membrane protein; Similar to Corynebacterium ammoniagenes hypothetical protein Orf1 TR:Q9RHY4 (EMBL:AB003158) (245 aa) fasta scores: E(): 3.5e-52, 56.65% id in 233 aa, and to Streptomyces coelicolor conserved hypothetical membrane protein 2SCK36.01c TR:CAC40591 (EMBL:AL591857) (234 aa) fasta scores: E(): 2.2e-26, 38.62% id in 233 aa.
       0.529
DIP0399
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 10.7 kDa protein Rv0508 or MT0529 or MTCY20G9.35 SW:Y508_MYCTU (Q11172) (97 aa) fasta scores: E(): 2.7e-08, 40.74% id in 81 aa.
  
  
 0.471
DIP0823
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT3292 TR:AAK47635 (EMBL:AE007142) (84 aa) fasta scores: E(): 4.4e-12, 48.1% id in 79 aa.
  
  
 0.471
rpmD
Similar to Streptomyces coelicolor 50S ribosomal protein L30 RpmD or SCD31.45 SW:RL30_STRCO (P46789) (60 aa) fasta scores: E(): 2.1e-08, 53.57% id in 56 aa.
      
 0.421
nusG
Putative transcription antitermination protein; Participates in transcription elongation, termination and antitermination.
      
 0.420
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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