STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1929Similar to Thermus aquaticus aspartate aminotransferase AspC SW:AAT_THETH (Q56232) (385 aa) fasta scores: E(): 1.1e-29, 32.95% id in 352 aa, and to Mycobacterium tuberculosis hypothetical protein Rv3565 TR:P96847 (EMBL:Z92774) (388 aa) fasta scores: E(): 6.4e-68, 48.15% id in 380 aa. (378 aa)    
Predicted Functional Partners:
purB
Similar to Homo sapiens adenylosuccinate lyase AdsL SW:PUR8_HUMAN (P30566) (484 aa) fasta scores: E(): 3.3e-39, 33.19% id in 470 aa, and to Corynebacterium ammoniagenes adenylosuccino lyase PurB TR:Q9RHX3 (EMBL:AB003161) (479 aa) fasta scores: E(): 4.4e-148, 82.91% id in 480 aa.
  
 
 0.858
DIP1930
Conserved hypothetical protein; Similar to Bacillus halodurans potassium uptake protein BH2663 TR:Q9K9I4 (EMBL:AP001516) (220 aa) fasta scores: E(): 1.2e-20, 34.29% id in 207 aa, and to Staphylococcus aureus (strain N315) hypothetical protein SA0939 TR:Q99V10 (EMBL:AP003132) (220 aa) fasta scores: E(): 4.6e-20, 35.09% id in 208 aa.
  
    0.832
DIP1931
Sodium transport protein; Similar to Enterococcus hirae V-type sodium ATP synthase subunit J NtpJ SW:NTPJ_ENTHR (P43440) (451 aa) fasta scores: E(): 3.8e-45, 36.94% id in 452 aa, and to Synechocystis sp Na+-ATPase subunit J SLR1509 TR:P73949 (EMBL:D90911) (444 aa) fasta scores: E(): 4.3e-49, 39.68% id in 446 aa.
       0.825
purD
Similar to Escherichia coli phosphoribosylamine--glycine ligase PurD SW:PUR2_ECOLI (P15640) (429 aa) fasta scores: E(): 5.9e-59, 43.75% id in 432 aa, and to Corynebacterium ammoniagenes 5'-phosphoribosylglycinamide synthetase PurD TR:Q9RHX4 (EMBL:AB003161) (426 aa) fasta scores: E(): 1.9e-110, 69.46% id in 429 aa; Belongs to the GARS family.
   
 
 0.711
purC
Putative phosphoribosylaminoimidazole-succinocarboxamide synthase; Similar to Saccharomyces cerevisiae phosphoribosylamidoimidazole-succinocarboxamide synthase ADE1 SW:PUR7_YEAST (P27616) (306 aa) fasta scores: E(): 7.6e-34, 44.06% id in 295 aa, and to Corynebacterium ammoniagenes 5'-phosphoribosyl-4-N-succinocarboxamide-5-amino imidazole synthetase PurC TR:Q9RHX2 (EMBL:AB003161) (295 aa) fasta scores: E(): 2e-89, 75.84% id in 294 aa.
  
    0.704
DIP1238
Putative dipeptidase; Similar to Mycobacterium tuberculosis probable dipeptidase Rv2089c or MT2150 or MTCY49.29c SWALL:YK89_MYCTU (SWALL:Q10698) (375 aa) fasta scores: E(): 3.1e-56, 49.86% id in 377 aa, and to Halobacterium sp probable peptidase PepQ1 or Vng0723g SWALL:Q9HRF6 (EMBL:AE005016) (369 aa) fasta scores: E(): 2.2e-37, 38.62% id in 378 aa.
    
 
 0.618
DIP1933
HIT family protein; Similar to Rhodococcus sp. S9 HIT-like protein TR:Q9L4T6 (EMBL:AF265258) (141 aa) fasta scores: E(): 1.4e-24, 52.98% id in 134 aa, and to Mycobacterium leprae hypothetical HIT-like protein ML2237 SW:YHI1_MYCLE (P49774) (134 aa) fasta scores: E(): 1.1e-23, 50.37% id in 133 aa.
  
    0.608
lysC
Aspartokinase; Similar to Corynebacterium flavum aspartokinase LysC or Ask SW:AK_CORFL (P41398) (421 aa) fasta scores: E(): 1.8e-135, 87.64% id in 421 aa; Belongs to the aspartokinase family.
  
 0.589
asnB
Putative asparagine synthetase; Highly similar to Corynebacterium glutamicum LtsA TR:Q9LCB7 (EMBL:AB029550) (640 aa) fasta scores: E(): 0, 83.9% id in 640 aa, and to Bacillus subtilis asparagine synthetase [glutamine-hydrolyzing] 1 AsnB or Asn SW:ASNB_BACSU (P54420) (632 aa) fasta scores: E(): 2.8e-111, 49.76% id in 631 aa.
     
 0.545
aspA
Aspartate ammonia-lyase; Similar to Corynebacterium glutamicum aspartate ammonia-lyase AspA SWALL:ASPA_CORGL (SWALL:Q59200) (526 aa) fasta scores: E(): 1e-151, 75.66% id in 526 aa, and to Escherichia coli aspartate ammonia-lyase AspA or B4139 SWALL:ASPA_ECOLI (SWALL:P04422) (478 aa) fasta scores: E(): 5.2e-121, 67.16% id in 469 aa.
     
 0.543
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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