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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1931Sodium transport protein; Similar to Enterococcus hirae V-type sodium ATP synthase subunit J NtpJ SW:NTPJ_ENTHR (P43440) (451 aa) fasta scores: E(): 3.8e-45, 36.94% id in 452 aa, and to Synechocystis sp Na+-ATPase subunit J SLR1509 TR:P73949 (EMBL:D90911) (444 aa) fasta scores: E(): 4.3e-49, 39.68% id in 446 aa. (444 aa)    
Predicted Functional Partners:
DIP1930
Conserved hypothetical protein; Similar to Bacillus halodurans potassium uptake protein BH2663 TR:Q9K9I4 (EMBL:AP001516) (220 aa) fasta scores: E(): 1.2e-20, 34.29% id in 207 aa, and to Staphylococcus aureus (strain N315) hypothetical protein SA0939 TR:Q99V10 (EMBL:AP003132) (220 aa) fasta scores: E(): 4.6e-20, 35.09% id in 208 aa.
 
 
 0.989
purB
Similar to Homo sapiens adenylosuccinate lyase AdsL SW:PUR8_HUMAN (P30566) (484 aa) fasta scores: E(): 3.3e-39, 33.19% id in 470 aa, and to Corynebacterium ammoniagenes adenylosuccino lyase PurB TR:Q9RHX3 (EMBL:AB003161) (479 aa) fasta scores: E(): 4.4e-148, 82.91% id in 480 aa.
       0.838
DIP1929
Similar to Thermus aquaticus aspartate aminotransferase AspC SW:AAT_THETH (Q56232) (385 aa) fasta scores: E(): 1.1e-29, 32.95% id in 352 aa, and to Mycobacterium tuberculosis hypothetical protein Rv3565 TR:P96847 (EMBL:Z92774) (388 aa) fasta scores: E(): 6.4e-68, 48.15% id in 380 aa.
       0.825
DIP1750
Similar to Vibrio cholerae glutathione-regulated potassium-efflux system protein KefB, putative VC0992 TR:Q9KTB1 (EMBL:AE004180) (528 aa) fasta scores: E(): 1.3e-37, 33.26% id in 514 aa; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
 
 0.798
DIP0724
Similar to Mycobacterium tuberculosis CDC1551 transporter, putative MT3294 TR:AAK47637 (EMBL:AE007142) (355 aa) fasta scores: E(): 2.5e-75, 61.78% id in 348 aa, and to Escherichia coli putative potassium channel protein Kch or B1250 SW:KCH_ECOLI (P31069) (417 aa) fasta scores: E(): 1.5e-07, 26.06% id in 234 aa.
  
 
 0.725
purD
Similar to Escherichia coli phosphoribosylamine--glycine ligase PurD SW:PUR2_ECOLI (P15640) (429 aa) fasta scores: E(): 5.9e-59, 43.75% id in 432 aa, and to Corynebacterium ammoniagenes 5'-phosphoribosylglycinamide synthetase PurD TR:Q9RHX4 (EMBL:AB003161) (426 aa) fasta scores: E(): 1.9e-110, 69.46% id in 429 aa; Belongs to the GARS family.
       0.702
purC
Putative phosphoribosylaminoimidazole-succinocarboxamide synthase; Similar to Saccharomyces cerevisiae phosphoribosylamidoimidazole-succinocarboxamide synthase ADE1 SW:PUR7_YEAST (P27616) (306 aa) fasta scores: E(): 7.6e-34, 44.06% id in 295 aa, and to Corynebacterium ammoniagenes 5'-phosphoribosyl-4-N-succinocarboxamide-5-amino imidazole synthetase PurC TR:Q9RHX2 (EMBL:AB003161) (295 aa) fasta scores: E(): 2e-89, 75.84% id in 294 aa.
       0.597
DIP0293
Putative Na+/H+ antiporter subunit; Similar to Pseudomonas aeruginosa probable NADH dehydrogenase PA1054 TR:Q9I4S0 (EMBL:AE004537) (933 aa) fasta scores: E(): 3e-85, 34.395% id in 942 aa, and to Rhizobium meliloti pH adaptation potassium efflux system transmembrane protein TR:CAC47489 (EMBL:AL591792) (999 aa) fasta scores: E(): 5.9e-61, 31.818% id in 968 aa, and to Staphylococcus aureus Na+/H+ antiporter subunit MnhA TR:Q9ZNG6 (EMBL:AB015981) (801 aa) fasta scores: E(): 6.5e-33, 31.750% id in 800 aa.
     
 0.534
DIP1933
HIT family protein; Similar to Rhodococcus sp. S9 HIT-like protein TR:Q9L4T6 (EMBL:AF265258) (141 aa) fasta scores: E(): 1.4e-24, 52.98% id in 134 aa, and to Mycobacterium leprae hypothetical HIT-like protein ML2237 SW:YHI1_MYCLE (P49774) (134 aa) fasta scores: E(): 1.1e-23, 50.37% id in 133 aa.
       0.521
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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