STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1947Integrase; N-terminus is identical to the N-terminal regions of Mycobacterium fortuitum integrase Orf2M TR:Q49186 (EMBL:X53635) (303 aa) fasta scores: E(): 3.6e-79, 100% id in 194 aa, and Acinetobacter baumannii integraseTtnp1 TR:AAA56784 (EMBL:U17586) (337 aa) fasta scores: E(): 4e-79, 100% id in 194 aa. (221 aa)    
Predicted Functional Partners:
DIP1948
Putative dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
     0.745
DIP1949
Putative acetyltransferase; Identical to Escherichia coli hypothetical protein YbbA TR:P75025 (EMBL:U12441) (166 aa) fasta scores: E(): 1.6e-70, 100% id in 166 aa, and to Acinetobacter baumannii hypothetical protein TR:AAK72477 (EMBL:AY038837) (142 aa) fasta scores: E(): 4.2e-59, 100% id in 142 aa.
 
     0.735
xerC
Putative integrase/recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
 
     0.441
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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