Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DIP1966Putative glycosyltransferase; Similar to Schizosaccharomyces pombe alpha,alpha-trehalose-phosphate synthase [UDP-forming] TPS1 SW:TPS1_SCHPO (P40387) (513 aa) fasta scores: E(): 7e-55, 36.68% id in 477 aa, and to Mycobacterium tuberculosis alpha,alpha-trehalose-phosphate synthase Rv3490 TR:O06353 (EMBL:Z95390) (500 aa) fasta scores: E(): 3.1e-98, 55.18% id in 482 aa. (479 aa)    
Predicted Functional Partners:
DIP1968
Putative trehalose-phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
 
 0.999
DIP0862
Putative urydyltransferase; Similar to Mycobacterium tuberculosis CDC1551 UTP--glucose-1-phosphate uridylyltransferase MT1022 TR:AAK45269 (EMBL:AE006986) (306 aa) fasta scores: E(): 3.2e-65, 64.8% id in 287 aa, and to Bacillus subtilis UTP--glucose-1-phosphate uridylyltransferase GtaB SW:GTAB_BACSU (Q05852) (292 aa) fasta scores: E(): 1.4e-32, 40.67% id in 295 aa.
    
 0.940
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
     
 0.903
DIP1965
Hypothetical protein; Limited database matches. Similar to Chlamydia muridarum histone H1-like protein TC0119 SW:HCT1_CHLMU (Q9PLI1) (125 aa) fasta scores: E(): 0.19, 35.39% id in 113 aa, and to Chlamydia trachomatis histone H1-like protein CT743 SW:HCT1_CHLTR (Q02281) (125 aa) fasta scores: E(): 0.22, 35.39% id in 113 aa. CDS contains a C-terminal lysine rich region.
  
  
 0.895
DIP1967
Putative exported protein; No significant database matches.
  
    0.768
DIP0533
Putative glycosilase; Similar to Bacillus coagulans oligo-1,6-glucosidase MalL SW:O16G_BACCO (Q45101) (555 aa) fasta scores: E(): 1.3e-26, 30.98% id in 539 aa.
  
  
 0.710
DIP1964
Similar to Corynebacterium glutamicum ThrEonine export carrier protein ThrE TR:AAK61331 (EMBL:AF326510) (489 aa) fasta scores: E(): 7e-110, 63.45% id in 487 aa, and to Mycobacterium tuberculosis putative membrane protein Rv3737 TR:O69704 (EMBL:AL022121) (529 aa) fasta scores: E(): 1.6e-37, 36.1% id in 421 aa. Note: Also similar to DIP1953 (483 aa) fasta scores: E(): 3.6e-61, 44.662% identity in 459 aa overlap.
       0.710
fas
Putative fatty acid synthase; Similar to the N-terminal region of Corynebacterium ammoniagenes fatty acid synthase Fas TR:Q04846 (EMBL:X64795) (3104 aa) fasta scores: E(): 0, 61.33% id in 3018 aa, and to the full length of Mycobacterium tuberculosis fatty acid synthase Rv2524c TR:AAK46907 (EMBL:Z83863) (3069 aa) fasta scores: E(): 1e-197, 51.37% id in 3083 aa, and of Corynebacterium glutamicum 3-oxoacyl-(acyl-carrier-protein) synthase CGL2495 SWALL:Q8NMS0 (EMBL:AP005281) (2993 aa) fasta scores: E(): 0, 67.35% id in 3008 aa.
      
 0.672
murG
UDP-N-acetylglucosamine-N-acetylmuramyl (pentapeptide); Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
      
 0.668
murB
Putative peptidoglycan synthesis related protein; Cell wall formation.
      
 0.661
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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