| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DIP0994 | DIP1974 | DIP0994 | DIP1974 | Similar to Mycobacterium avium putative RNA polymerase sigma factor SigE TR:O05735 (EMBL:U87308) (251 aa) fasta scores: E(): 1.2e-47, 62.33% id in 223 aa, and to Bacillus subtilis RNA polymerase sigma factor SigW SW:SIGW_BACSU (Q45585) (187 aa) fasta scores: E(): 4.2e-13, 32.36% id in 173 aa; Belongs to the sigma-70 factor family. ECF subfamily. | Putative CarD-like transcriptional factor; N-terminal region is similar to Mycobacterium tuberculosis putative transcriptional factor Rv3583c TR:O53568 (EMBL:AL022075) (162 aa) fasta scores: E(): 6.8e-38, 71.69% id in 159 aa, and to Mycobacterium leprae putative transcription factor ML0320 TR:Q9CCW7 (EMBL:AL583918) (165 aa) fasta scores: E(): 1.2e-37, 70.44% id in 159 aa. | 0.866 |
| DIP0994 | rpoA | DIP0994 | DIP0549 | Similar to Mycobacterium avium putative RNA polymerase sigma factor SigE TR:O05735 (EMBL:U87308) (251 aa) fasta scores: E(): 1.2e-47, 62.33% id in 223 aa, and to Bacillus subtilis RNA polymerase sigma factor SigW SW:SIGW_BACSU (Q45585) (187 aa) fasta scores: E(): 4.2e-13, 32.36% id in 173 aa; Belongs to the sigma-70 factor family. ECF subfamily. | DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.748 |
| DIP0994 | rpoB | DIP0994 | DIP0446 | Similar to Mycobacterium avium putative RNA polymerase sigma factor SigE TR:O05735 (EMBL:U87308) (251 aa) fasta scores: E(): 1.2e-47, 62.33% id in 223 aa, and to Bacillus subtilis RNA polymerase sigma factor SigW SW:SIGW_BACSU (Q45585) (187 aa) fasta scores: E(): 4.2e-13, 32.36% id in 173 aa; Belongs to the sigma-70 factor family. ECF subfamily. | DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.866 |
| DIP0994 | rpoC | DIP0994 | DIP0447 | Similar to Mycobacterium avium putative RNA polymerase sigma factor SigE TR:O05735 (EMBL:U87308) (251 aa) fasta scores: E(): 1.2e-47, 62.33% id in 223 aa, and to Bacillus subtilis RNA polymerase sigma factor SigW SW:SIGW_BACSU (Q45585) (187 aa) fasta scores: E(): 4.2e-13, 32.36% id in 173 aa; Belongs to the sigma-70 factor family. ECF subfamily. | DNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.866 |
| DIP0994 | rpoZ | DIP0994 | DIP1327 | Similar to Mycobacterium avium putative RNA polymerase sigma factor SigE TR:O05735 (EMBL:U87308) (251 aa) fasta scores: E(): 1.2e-47, 62.33% id in 223 aa, and to Bacillus subtilis RNA polymerase sigma factor SigW SW:SIGW_BACSU (Q45585) (187 aa) fasta scores: E(): 4.2e-13, 32.36% id in 173 aa; Belongs to the sigma-70 factor family. ECF subfamily. | Putative DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.713 |
| DIP1974 | DIP0994 | DIP1974 | DIP0994 | Putative CarD-like transcriptional factor; N-terminal region is similar to Mycobacterium tuberculosis putative transcriptional factor Rv3583c TR:O53568 (EMBL:AL022075) (162 aa) fasta scores: E(): 6.8e-38, 71.69% id in 159 aa, and to Mycobacterium leprae putative transcription factor ML0320 TR:Q9CCW7 (EMBL:AL583918) (165 aa) fasta scores: E(): 1.2e-37, 70.44% id in 159 aa. | Similar to Mycobacterium avium putative RNA polymerase sigma factor SigE TR:O05735 (EMBL:U87308) (251 aa) fasta scores: E(): 1.2e-47, 62.33% id in 223 aa, and to Bacillus subtilis RNA polymerase sigma factor SigW SW:SIGW_BACSU (Q45585) (187 aa) fasta scores: E(): 4.2e-13, 32.36% id in 173 aa; Belongs to the sigma-70 factor family. ECF subfamily. | 0.866 |
| DIP1974 | ispD | DIP1974 | DIP1973 | Putative CarD-like transcriptional factor; N-terminal region is similar to Mycobacterium tuberculosis putative transcriptional factor Rv3583c TR:O53568 (EMBL:AL022075) (162 aa) fasta scores: E(): 6.8e-38, 71.69% id in 159 aa, and to Mycobacterium leprae putative transcription factor ML0320 TR:Q9CCW7 (EMBL:AL583918) (165 aa) fasta scores: E(): 1.2e-37, 70.44% id in 159 aa. | Putative 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.916 |
| DIP1974 | ispF | DIP1974 | DIP1972 | Putative CarD-like transcriptional factor; N-terminal region is similar to Mycobacterium tuberculosis putative transcriptional factor Rv3583c TR:O53568 (EMBL:AL022075) (162 aa) fasta scores: E(): 6.8e-38, 71.69% id in 159 aa, and to Mycobacterium leprae putative transcription factor ML0320 TR:Q9CCW7 (EMBL:AL583918) (165 aa) fasta scores: E(): 1.2e-37, 70.44% id in 159 aa. | Putative 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.836 |
| DIP1974 | rbpA | DIP1974 | DIP1225 | Putative CarD-like transcriptional factor; N-terminal region is similar to Mycobacterium tuberculosis putative transcriptional factor Rv3583c TR:O53568 (EMBL:AL022075) (162 aa) fasta scores: E(): 6.8e-38, 71.69% id in 159 aa, and to Mycobacterium leprae putative transcription factor ML0320 TR:Q9CCW7 (EMBL:AL583918) (165 aa) fasta scores: E(): 1.2e-37, 70.44% id in 159 aa. | Conserved hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family. | 0.969 |
| DIP1974 | rpoA | DIP1974 | DIP0549 | Putative CarD-like transcriptional factor; N-terminal region is similar to Mycobacterium tuberculosis putative transcriptional factor Rv3583c TR:O53568 (EMBL:AL022075) (162 aa) fasta scores: E(): 6.8e-38, 71.69% id in 159 aa, and to Mycobacterium leprae putative transcription factor ML0320 TR:Q9CCW7 (EMBL:AL583918) (165 aa) fasta scores: E(): 1.2e-37, 70.44% id in 159 aa. | DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.936 |
| DIP1974 | rpoB | DIP1974 | DIP0446 | Putative CarD-like transcriptional factor; N-terminal region is similar to Mycobacterium tuberculosis putative transcriptional factor Rv3583c TR:O53568 (EMBL:AL022075) (162 aa) fasta scores: E(): 6.8e-38, 71.69% id in 159 aa, and to Mycobacterium leprae putative transcription factor ML0320 TR:Q9CCW7 (EMBL:AL583918) (165 aa) fasta scores: E(): 1.2e-37, 70.44% id in 159 aa. | DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.963 |
| DIP1974 | rpoC | DIP1974 | DIP0447 | Putative CarD-like transcriptional factor; N-terminal region is similar to Mycobacterium tuberculosis putative transcriptional factor Rv3583c TR:O53568 (EMBL:AL022075) (162 aa) fasta scores: E(): 6.8e-38, 71.69% id in 159 aa, and to Mycobacterium leprae putative transcription factor ML0320 TR:Q9CCW7 (EMBL:AL583918) (165 aa) fasta scores: E(): 1.2e-37, 70.44% id in 159 aa. | DNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.955 |
| DIP1974 | rpoZ | DIP1974 | DIP1327 | Putative CarD-like transcriptional factor; N-terminal region is similar to Mycobacterium tuberculosis putative transcriptional factor Rv3583c TR:O53568 (EMBL:AL022075) (162 aa) fasta scores: E(): 6.8e-38, 71.69% id in 159 aa, and to Mycobacterium leprae putative transcription factor ML0320 TR:Q9CCW7 (EMBL:AL583918) (165 aa) fasta scores: E(): 1.2e-37, 70.44% id in 159 aa. | Putative DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.946 |
| DIP1974 | sigA | DIP1974 | DIP1406 | Putative CarD-like transcriptional factor; N-terminal region is similar to Mycobacterium tuberculosis putative transcriptional factor Rv3583c TR:O53568 (EMBL:AL022075) (162 aa) fasta scores: E(): 6.8e-38, 71.69% id in 159 aa, and to Mycobacterium leprae putative transcription factor ML0320 TR:Q9CCW7 (EMBL:AL583918) (165 aa) fasta scores: E(): 1.2e-37, 70.44% id in 159 aa. | RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.878 |
| DIP1974 | sigB | DIP1974 | DIP1413 | Putative CarD-like transcriptional factor; N-terminal region is similar to Mycobacterium tuberculosis putative transcriptional factor Rv3583c TR:O53568 (EMBL:AL022075) (162 aa) fasta scores: E(): 6.8e-38, 71.69% id in 159 aa, and to Mycobacterium leprae putative transcription factor ML0320 TR:Q9CCW7 (EMBL:AL583918) (165 aa) fasta scores: E(): 1.2e-37, 70.44% id in 159 aa. | RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.878 |
| ispD | DIP1974 | DIP1973 | DIP1974 | Putative 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | Putative CarD-like transcriptional factor; N-terminal region is similar to Mycobacterium tuberculosis putative transcriptional factor Rv3583c TR:O53568 (EMBL:AL022075) (162 aa) fasta scores: E(): 6.8e-38, 71.69% id in 159 aa, and to Mycobacterium leprae putative transcription factor ML0320 TR:Q9CCW7 (EMBL:AL583918) (165 aa) fasta scores: E(): 1.2e-37, 70.44% id in 159 aa. | 0.916 |
| ispD | ispF | DIP1973 | DIP1972 | Putative 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | Putative 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.999 |
| ispF | DIP1974 | DIP1972 | DIP1974 | Putative 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | Putative CarD-like transcriptional factor; N-terminal region is similar to Mycobacterium tuberculosis putative transcriptional factor Rv3583c TR:O53568 (EMBL:AL022075) (162 aa) fasta scores: E(): 6.8e-38, 71.69% id in 159 aa, and to Mycobacterium leprae putative transcription factor ML0320 TR:Q9CCW7 (EMBL:AL583918) (165 aa) fasta scores: E(): 1.2e-37, 70.44% id in 159 aa. | 0.836 |
| ispF | ispD | DIP1972 | DIP1973 | Putative 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | Putative 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.999 |
| rbpA | DIP1974 | DIP1225 | DIP1974 | Conserved hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family. | Putative CarD-like transcriptional factor; N-terminal region is similar to Mycobacterium tuberculosis putative transcriptional factor Rv3583c TR:O53568 (EMBL:AL022075) (162 aa) fasta scores: E(): 6.8e-38, 71.69% id in 159 aa, and to Mycobacterium leprae putative transcription factor ML0320 TR:Q9CCW7 (EMBL:AL583918) (165 aa) fasta scores: E(): 1.2e-37, 70.44% id in 159 aa. | 0.969 |