Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DIP1986Conserved hypothetical protein; Similar to Homo sapiens monoglyceride lipase TR:CAC43316 (EMBL:AJ270950) (303 aa) fasta scores: E(): 1.6e-14, 28.88% id in 277 aa, and to Deinococcus radiodurans putative lipase putative DR1537 TR:Q9RU57 (EMBL:AE001997) (282 aa) fasta scores: E(): 4.2e-24, 33.69% id in 276 aa. (282 aa)    
Predicted Functional Partners:
DIP1985
Putative membrane protein; Poor database matches. C-terminal region is similar to Rhizobium loti hypothetical protein MLL0061 TR:Q98NN3 (EMBL:AP002994) (97 aa) fasta scores: E(): 1.7, 25% id in 96 aa. Possible alternative translational start site.
       0.608
DIP2160
Modular polyketide synthase; Similar to Streptomyces verticillus polyketide synthase BlmVIII (bleomycin biosynthesis) TR:Q9FB25 (EMBL:AF210249) (1841 aa) fasta scores: E(): 1.3e-72, 27.240% id in 1931 aa, and to Streptomyces noursei nystatin biosynthesis polyketide synthase Nys TR:Q9L4W3 (EMBL:AF263912) (11096 aa) fasta scores: E(): 4e-71, 33.107% id in 882 aa, and to Amycolatopsis mediterranei rifamycin polyketide synthase TR:Q9F847 (EMBL:AF262754) (1265 aa) fasta scores: E(): 7.7e-61, 31.042% id in 902 aa.
  
 
 0.591
DIP1984
Similar to Pasteurella multocida hypothetical protein PM0821 TR:Q9CMK3 (EMBL:AE006121) (150 aa) fasta scores: E(): 8.8e-19, 46% id in 150 aa, and to Deinococcus radiodurans conserved hypothetical protein DR1979 TR:Q9RSZ0 (EMBL:AE002036) (161 aa) fasta scores: E(): 8.6e-16, 42.66% id in 150 aa.
       0.453
DIP2189
Putative polyketide synthase; Similar to Mycobacterium tuberculosis polyketide synthase PKS13 or Rv3800c or MTV026.05c TR:O53579 (EMBL:AL022076) (1733 aa) fasta scores: E(): 5.4e-109, 44.5% id in 1719 aa, and to Polyangium cellulosum soraphen polyketide synthase A SorA TR:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 6.2e-101, 35.96% id in 1090 aa.
   
 
 0.447
DIP0326
Conserved hypothetical protein; Similar to Streptomyces coelicolor putative oxidoreductase SCF43A.31 TR:Q9XA84 (EMBL:AL096837) (520 aa) fasta scores: E(): 7.8e-84, 44.21% id in 484 aa.
  
   0.443
DIP1083
Similar to Streptomyces coelicolor putative membrane protein SCE6.24 TR:Q9KZR4 (EMBL:AL353832) (100 aa) fasta scores: E(): 4.1e-13, 49.47% id in 95 aa.
  
   0.443
fas
Putative fatty acid synthase; Similar to the N-terminal region of Corynebacterium ammoniagenes fatty acid synthase Fas TR:Q04846 (EMBL:X64795) (3104 aa) fasta scores: E(): 0, 61.33% id in 3018 aa, and to the full length of Mycobacterium tuberculosis fatty acid synthase Rv2524c TR:AAK46907 (EMBL:Z83863) (3069 aa) fasta scores: E(): 1e-197, 51.37% id in 3083 aa, and of Corynebacterium glutamicum 3-oxoacyl-(acyl-carrier-protein) synthase CGL2495 SWALL:Q8NMS0 (EMBL:AP005281) (2993 aa) fasta scores: E(): 0, 67.35% id in 3008 aa.
     
 0.408
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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