STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1986Conserved hypothetical protein; Similar to Homo sapiens monoglyceride lipase TR:CAC43316 (EMBL:AJ270950) (303 aa) fasta scores: E(): 1.6e-14, 28.88% id in 277 aa, and to Deinococcus radiodurans putative lipase putative DR1537 TR:Q9RU57 (EMBL:AE001997) (282 aa) fasta scores: E(): 4.2e-24, 33.69% id in 276 aa. (282 aa)    
Predicted Functional Partners:
DIP1985
Putative membrane protein; Poor database matches. C-terminal region is similar to Rhizobium loti hypothetical protein MLL0061 TR:Q98NN3 (EMBL:AP002994) (97 aa) fasta scores: E(): 1.7, 25% id in 96 aa. Possible alternative translational start site.
       0.608
DIP2160
Modular polyketide synthase; Similar to Streptomyces verticillus polyketide synthase BlmVIII (bleomycin biosynthesis) TR:Q9FB25 (EMBL:AF210249) (1841 aa) fasta scores: E(): 1.3e-72, 27.240% id in 1931 aa, and to Streptomyces noursei nystatin biosynthesis polyketide synthase Nys TR:Q9L4W3 (EMBL:AF263912) (11096 aa) fasta scores: E(): 4e-71, 33.107% id in 882 aa, and to Amycolatopsis mediterranei rifamycin polyketide synthase TR:Q9F847 (EMBL:AF262754) (1265 aa) fasta scores: E(): 7.7e-61, 31.042% id in 902 aa.
  
 
 0.559
DIP0326
Conserved hypothetical protein; Similar to Streptomyces coelicolor putative oxidoreductase SCF43A.31 TR:Q9XA84 (EMBL:AL096837) (520 aa) fasta scores: E(): 7.8e-84, 44.21% id in 484 aa.
  
   0.554
DIP1083
Similar to Streptomyces coelicolor putative membrane protein SCE6.24 TR:Q9KZR4 (EMBL:AL353832) (100 aa) fasta scores: E(): 4.1e-13, 49.47% id in 95 aa.
  
   0.554
DIP2189
Putative polyketide synthase; Similar to Mycobacterium tuberculosis polyketide synthase PKS13 or Rv3800c or MTV026.05c TR:O53579 (EMBL:AL022076) (1733 aa) fasta scores: E(): 5.4e-109, 44.5% id in 1719 aa, and to Polyangium cellulosum soraphen polyketide synthase A SorA TR:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 6.2e-101, 35.96% id in 1090 aa.
  
 
 0.510
DIP2161
Nonribosomal peptide synthase; Similar to Stigmatella aurantiaca myxothiazol synthase MtaC TR:Q9RFK9 (EMBL:AF188287) (1290 aa) fasta scores: E(): 1.7e-86, 35.694% id in 1073 aa, and to Polyangium cellulosum epothilone biosynthase EpoB TR:Q9KIZ9 (EMBL:AF217189) (1410 aa) fasta scores: E(): 1.8e-81, 35.385% id in 975 aa, and to Pseudomonas aeruginosa pyochelin synthetase PchF or PA4225 TR:Q9HWG4 (EMBL:AE004839) (1809 aa) fasta scores: E(): 1.9e-81, 37.017% id in 932 aa.
  
 
 0.492
DIP1984
Similar to Pasteurella multocida hypothetical protein PM0821 TR:Q9CMK3 (EMBL:AE006121) (150 aa) fasta scores: E(): 8.8e-19, 46% id in 150 aa, and to Deinococcus radiodurans conserved hypothetical protein DR1979 TR:Q9RSZ0 (EMBL:AE002036) (161 aa) fasta scores: E(): 8.6e-16, 42.66% id in 150 aa.
       0.453
DIP1768
Conserved hypothetical protein; Similar to Streptomyces coelicolor putative ankyrin-like protein SC6D7.25 TR:Q9RKX3 (EMBL:AL133213) (134 aa) fasta scores: E(): 4.4e-23, 57.36% id in 129 aa, and to Campylobacter jejuni ankyrin-repeat containing protein Cj1386 TR:Q9PMR4 (EMBL:AL139078) (156 aa) fasta scores: E(): 1.2e-10, 39.66% id in 121 aa.
    
   0.433
DIP1692
Similar to Thermotoga maritima acyl carrier protein TM0662 TR:Q9WZD0 (EMBL:AE001739) (81 aa) fasta scores: E(): 0.0012, 32.05% id in 78 aa, and to Bacillus halodurans acyl carrier protein AcpA or BH2490 SW:ACP_BACHD (Q9KA04) (77 aa) fasta scores: E(): 0.0062, 32.87% id in 73 aa.
  
   0.428
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
   0.409
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: low (36%) [HD]