STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1991Putative membrane protein; Similar to Streptomyces coelicolor putative transmembrane protein SCK7.11c TR:Q9KIM1 (EMBL:AF230489) (312 aa) fasta scores: E(): 4.5e-47, 50.16% id in 301 aa. C-terminal region is similar to Streptococcus pneumoniae hypothetical protein SP2132 TR:AAK76190 (EMBL:AE007502) (335 aa) fasta scores: E(): 8.7e-22, 42.43% id in 304 aa. (322 aa)    
Predicted Functional Partners:
ftsH
Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.863
DIP1276
Putative secreted protein; Similar to Mycobacterium tuberculosis hypothetical 41.2 kDa protein Rv1488 or MT1533.2 or MTCY277.09 SWALL:YE88_MYCTU (SWALL:P71768) (381 aa) fasta scores: E(): 1.4e-79, 62.53% id in 363 aa, and to Pyrococcus abyssi stomatin-like protein PAB1324 SWALL:Q9UYE4 (EMBL:AJ248288) (299 aa) fasta scores: E(): 2.7e-35, 42.65% id in 279 aa.
      
 0.861
DIP1992
Sodium:dicarboxylate symporter family; C-terminal region is similar to Escherichia coli proton glutamate symport protein GltP SW:GLTP_ECOLI (P21345) (437 aa) fasta scores: E(): 2.5e-34, 29.25% id in 417 aa, and to the C-terminal region of Caulobacter crescentus sodium:dicarboxylate symporter family protein CC1104 TR:Q9A990 (EMBL:AE005788) (476 aa) fasta scores: E(): 1.4e-90, 57.93% id in 435 aa. Possible alternative translational start site; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
   
 0.701
DIP0134
Putative DNA-repair protein; Similar to Mycobacterium tuberculosis CDC1551 DNA-3-methyladenine glycosidase I MT1248 TR:AAK45505 (EMBL:AE007001) (204 aa) fasta scores: E(): 8.3e-35, 52.71% id in 184 aa, and to Escherichia coli DNA-3-methyladenine glycosylase I Tag or B3549 SW:3MG1_ECOLI (P05100) (187 aa) fasta scores: E(): 1.5e-25, 44.88% id in 176 aa.
  
    0.663
arc
Putative AAA protein family ATPase; Similar to, although shorter in its N-terminal region than Streptomyces coelicolor AAA protein family ATPase Arc SWALL:Q9RJ58 (EMBL:AL132648) (588 aa) fasta scores: E(): 3e-76, 54.14% id in 519 aa, and to, although shorter in its N-terminal region than Mycobacterium leprae putative AAA-family ATPase ML1316 or MLCB2533.12 or A2126A or B2126_C1_167 SWALL:YL15_MYCLE (SWALL:P46509) (609 aa) fasta scores: E(): 2.1e-58, 54.99% id in 531 aa.
   
 
 0.476
fas
Putative fatty acid synthase; Similar to the N-terminal region of Corynebacterium ammoniagenes fatty acid synthase Fas TR:Q04846 (EMBL:X64795) (3104 aa) fasta scores: E(): 0, 61.33% id in 3018 aa, and to the full length of Mycobacterium tuberculosis fatty acid synthase Rv2524c TR:AAK46907 (EMBL:Z83863) (3069 aa) fasta scores: E(): 1e-197, 51.37% id in 3083 aa, and of Corynebacterium glutamicum 3-oxoacyl-(acyl-carrier-protein) synthase CGL2495 SWALL:Q8NMS0 (EMBL:AP005281) (2993 aa) fasta scores: E(): 0, 67.35% id in 3008 aa.
  
 
 0.454
DIP0027
Putative membrane protein; Similar to Mycobacterium tuberculosis putative transmembrane protein Rv0110 or MTV031.04 TR:O53632 (EMBL:AL021926) (249 aa) fasta scores: E(): 1.4e-13, 34.19% id in 193 aa.
   
 0.450
DIP1854
Putative membrane protein; Similar to Synechocystis sp. hypothetical protein SLR1461 TR:P74553 (EMBL:D90916) (198 aa) fasta scores: E(): 3e-21, 38.95% id in 172 aa, and to Bacillus halodurans hypothetical protein BH0517 TR:Q9KFG2 (EMBL:AP001508) (248 aa) fasta scores: E(): 3.1e-05, 29.1% id in 189 aa.
   
 0.450
lysU
Putative lysyl-tRNA synthetase; Similar to Escherichia coli heat inducible lysyl-tRNA synthetase LysU SW:SYK2_ECOLI (P14825) (504 aa) fasta scores: E(): 4.5e-73, 40.8% id in 522 aa, and to Mycobacterium tuberculosis lysyl-tRNA synthetase 1 Rv3598c SW:SYK1_MYCTU (O06284) (505 aa) fasta scores: E(): 3.9e-118, 61.87% id in 522 aa; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
   0.416
DIP2367
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 21.8 kDa protein Rv0038 or MT0043 or MTCY10h4.38 SW:Y038_MYCTU (P71608) (202 aa) fasta scores: E(): 4.4e-28, 43.64% id in 181 aa; Belongs to the UPF0301 (AlgH) family.
   
    0.407
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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