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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1992Sodium:dicarboxylate symporter family; C-terminal region is similar to Escherichia coli proton glutamate symport protein GltP SW:GLTP_ECOLI (P21345) (437 aa) fasta scores: E(): 2.5e-34, 29.25% id in 417 aa, and to the C-terminal region of Caulobacter crescentus sodium:dicarboxylate symporter family protein CC1104 TR:Q9A990 (EMBL:AE005788) (476 aa) fasta scores: E(): 1.4e-90, 57.93% id in 435 aa. Possible alternative translational start site; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (475 aa)    
Predicted Functional Partners:
DIP1991
Putative membrane protein; Similar to Streptomyces coelicolor putative transmembrane protein SCK7.11c TR:Q9KIM1 (EMBL:AF230489) (312 aa) fasta scores: E(): 4.5e-47, 50.16% id in 301 aa. C-terminal region is similar to Streptococcus pneumoniae hypothetical protein SP2132 TR:AAK76190 (EMBL:AE007502) (335 aa) fasta scores: E(): 8.7e-22, 42.43% id in 304 aa.
   
 0.701
ptsG
Similar to Corynebacterium glutamicum PTS system, glucose-specific IIABC component PtsG SWALL:PTGA_CORGL (SWALL:Q45298) (674 aa) fasta scores: E(): 2.8e-59, 44.91% id in 688 aa, and to Staphylococcus xylosus PTS system, sucrose-specific IIBC component ScrA SWALL:PTSB_STAXY (SWALL:P51184) (480 aa) fasta scores: E(): 8e-26, 27.73% id in 494 aa.
  
  
 0.596
DIP2349
Putative integral membrane transport protein; Similar to Treponema pallidum glutamate/aspartate transporter, putative tp0555 TR:O83566 (EMBL:AE001231) (396 aa) fasta scores: E(): 2.9e-33, 33.86% id in 375 aa; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
  
     0.596
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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