STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2010Similar to Actinomyces viscosus putative usher-like protein precursor TR:Q9AJ93 (EMBL:AF106034) (1411 aa) fasta scores: E(): 0.034, 22.657% id in 843 aa, and to Actinomyces naeslundii putative fimbrial associated protein TR:O05995 (EMBL:U85708) (375 aa) fasta scores: E(): 0.14, 25.131% id in 191 aa. Note: Contains a potential sortase anchor site (LPLTG) upstream of the C-terminal region transmembrane domain. (1872 aa)    
Predicted Functional Partners:
DIP2012
Putative fimbrial associated sortase-like protein; Similar to Actinomyces viscosus sortase-like protein SWALL:Q9AJ92 (EMBL:AF106034) (387 aa) fasta scores: E(): 2.7e-39, 43.47% id in 276 aa, and to Bifidobacterium longum NCC2705 sortase-like protein BL0676 SWALL:AAN24497 (EMBL:AE014690) (328 aa) fasta scores: E(): 3.7e-28, 36.94% id in 268 aa, and to Streptococcus pneumoniae sortase, putative SP0466 SWALL:AAK74626 (EMBL:AE007358) (279 aa) fasta scores: E(): 3e-21, 31.78% id in 258 aa.
 
     0.881
DIP2013
Similar to Actinomyces naeslundii fimbrial subunit type 2 precursor SW:FM2_ACTNA (P12616) (534 aa) fasta scores: E(): 4.4e-20, 28.827% id in 503 aa, and to Actinomyces naeslundii type-1 fimbrial major subunit precursor FimP TR:Q9X4D8 (EMBL:AF107019) (533 aa) fasta scores: E(): 8.5e-15, 27.432% id in 514 aa. Note: Contains a potential sortase anchor site (LPLTG) upstream of the C-terminal region transmembrane domain.
 
     0.870
DIP2011
Putative surface anchored protein; No significant database matches. Note: Contains a potential sortase anchor site (LAFTG) upstream of the C-terminal region transmembrane domain.
       0.773
DIP0736
Putative protease; C-terminal region similar to Drosophila erecta trypsin zeta precursor Try-ZetA SW:TRYZ_DROER (P54630) (281 aa) fasta scores: E(): 0.17, 26.03% id in 242 aa.
  
     0.732
DIP0737
Putative membrane protein; No significant database matches.
  
     0.687
DIP0674
Similar to Bradyrhizobium japonicum probable Ni/Fe-hydrogenase B-type cytochrome subunit HupC SW:CYBH_BRAJA (P21960) (244 aa) fasta scores: E(): 2.3e-16, 32.65% id in 245 aa, and to Escherichia coli probable Ni/Fe-hydrogenase 1 B-type cytochrome subunit HyaC or B0974 or Z1391 or ECS1130 SW:CYBH_ECOLI (P19929) (235 aa) fasta scores: E(): 6e-13, 30.04% id in 213 aa and N-terminal region similar to Homo sapiens vacuolar proton translocating ATPase 116 kDa subunit A isoform 2 SW:VPP2_HUMAN (Q9Y487) blast scores: E(): 2.6, score: 34 30% id.
  
     0.621
DIP2014
Putative membrane-anchored protein; No significant database matches.
       0.469
DIP0233
Similar to Actinomyces naeslundii putative fimbrial associated protein TR:O05996 (EMBL:U85709) (280 aa) fasta scores: E(): 4.5e-16, 40.000% id in 215 aa, and to Staphylococcus aureus sortase SrtA TR:Q9S446 (EMBL:AF162687) (206 aa) fasta scores: E(): 1.2, 26.923% id in 156 aa. Note: Also similar to DIP0236 (312 aa) E(): 5.7e-25; 45.342% identity in 322 aa overlap, DIP2224, DIP2012 and DIP2225.
  
     0.462
DIP0236
Similar to Actinomyces naeslundii putative fimbrial associated protein TR:O68213 (EMBL:AF019629) (365 aa) fasta scores: E(): 1.2e-31, 42.802% id in 257 aa, and to Staphylococcus aureus sortase SrtA TR:Q9S446 (EMBL:AF162687) (206 aa) fasta scores: E(): 0.094, 27.559% id in 127 aa. Note: Also similar to DIP0233 (329 aa) E(): 5.2e-25; 45.031% identity in 322 aa overlap. Note: Also similar to DIP2012, DIP2224 and DIP2225.
  
     0.462
DIP2224
Similar to Actinomyces naeslundii putative fimbriae-associated protein TR:O68213 (EMBL:AF019629) (365 aa) fasta scores: E(): 2.3e-33, 42.500% id in 280 aa, and to Staphylococcus aureus sortase SrtA TR:Q9S446 (EMBL:AF162687) (206 aa) fasta scores: E(): 0.0034, 26.115% id in 157 aa.
  
     0.448
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: medium (58%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.