Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DIP2025Similar to Pseudomonas aeruginosa hypothetical protein PA4583 SWALL:Q9HVK1 (EMBL:AE004872) (404 aa) fasta scores: E(): 7.5e-64, 45.92% id in 405 aa, and to Escherichia coli protein RtcB or B3421 SWALL:RTCB_ECOLI (SWALL:P46850) (408 aa) fasta scores: E(): 6e-45, 46.75% id in 385 aa. (434 aa)    
Predicted Functional Partners:
DIP2024
Hypothetical protein; No significant database matches.
       0.620
DIP0717
Similar to Mycobacterium leprae putative ATP-dependent RNA helicase RhlE or ML0811 TR:Q9CCH3 (EMBL:AL583919) (544 aa) fasta scores: E(): 2.1e-87, 55.78% id in 441 aa, and to Klebsiella pneumoniae cold-shock dead-box protein A DeaD or CsdA SW:DEAD_KLEPN (P33906) (642 aa) fasta scores: E(): 5.7e-49, 41.91% id in 377 aa.
   
  0.448
deaD
DEAD-box helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.
   
  0.448
DIP1212
Putative RNA helicase; Similar to Streptomyces coelicolor SC10A5.25c protein SWALL:O54116 (EMBL:AL021529) (498 aa) fasta scores: E(): 6.5e-63, 46.93% id in 424 aa, and to Escherichia coli putative ATP-dependent RNA helicase RhlE or B0797 SWALL:RHLE_ECOLI (SWALL:P25888) (454 aa) fasta scores: E(): 7.6e-44, 36.06% id in 452 aa.
   
  0.448
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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