STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2044Conserved hypothetical protein; Similar to Streptomyces coelicolor hypothetical 9.6 kDa protein SCD95A.20 SWALL:Q9KXV4 (EMBL:AL357432) (84 aa) fasta scores: E(): 1e-08, 54.09% id in 61 aa, and to Mycobacterium tuberculosis hypothetical 11.7 kDa protein Rv0430 or MT0445 or MTCY22G10.27 SWALL:P96276 (EMBL:Z84724) (102 aa) fasta scores: E(): 2.2e-07, 48.38% id in 62 aa. (67 aa)    
Predicted Functional Partners:
DIP2043
Putative secreted protein; No significant database matches.
  
    0.845
DIP2042
Conserved hypothetical protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
       0.842
DIP2046
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 32.6 kDa protein Rv0428c or MT0443 or MTCY22G10.25c SWALL:P96274 (EMBL:Z84724) (302 aa) fasta scores: E(): 2.7e-22, 34.53% id in 304 aa, and to Caulobacter crescentus acetyltransferase, GNAT family CC2209 SWALL:Q9A685 (EMBL:AE005892) (207 aa) fasta scores: E(): 2.4e-06, 30.76% id in 208 aa.
 
     0.750
def
Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
       0.715
DIP2047
Putative exonuclease; Similar to Streptomyces coelicolor putative exonuclease SC3A7.09 SWALL:O86610 (EMBL:AL031155) (259 aa) fasta scores: E(): 4.4e-32, 51.93% id in 258 aa, and to Mycobacterium tuberculosis CDC1551 exodeoxyribonuclease III MT0442 SWALL:AAK44665 (EMBL:AE006947) (291 aa) fasta scores: E(): 1.2e-25, 54.16% id in 264 aa.
       0.695
DIP2048
Putative cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
       0.695
DIP0823
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT3292 TR:AAK47635 (EMBL:AE007142) (84 aa) fasta scores: E(): 4.4e-12, 48.1% id in 79 aa.
  
     0.566
DIP1243
Conserved hypothetical protein; Similar to Rhodococcus erythropolis ORF11 SWALL:P72265 (EMBL:Z82004) (326 aa) fasta scores: E(): 1.3e-24, 31.42% id in 315 aa, and to Mycobacterium tuberculosis hypothetical 33.8 kDa protein Rv2095c precursor or MT2156 or MTCY49.35c SWALL:YK95_MYCTU (SWALL:Q10704) (316 aa) fasta scores: E(): 3.4e-24, 31.57% id in 304 aa.
  
     0.560
DIP1075
Similar to Mycobacterium leprae hypothetical protein ML1706 TR:Q9CBR6 (EMBL:AL583923) (337 aa) fasta scores: E(): 4.5e-19, 32.26% id in 313 aa, and to Mycobacterium tuberculosis CDC1551 vitamin-b12 independent methionine synthase family protein MT3095 TR:AAK47424 (EMBL:AE007129) (337 aa) fasta scores: E(): 1.4e-18, 31.94% id in 313 aa, and to Mycobacterium tuberculosis hypothetical 34.2 kDa protein Rv3015c or MTV012.29C TR:O53262 (EMBL:AL021287) (337 aa) fasta scores: E(): 1.4e-18, 31.94% id in 313 aa.
  
     0.459
DIP1733
Hypothetical protein; No significant database matches.
  
     0.419
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: medium (56%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.