STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2053Putative protein kinase; Similar to Mycobacterium tuberculosis probable serine/threonine-protein kinase PknG or Rv0410c or MT0423 or MTCY22G10.06c SWALL:PKNG_MYCTU (SWALL:P96256) (750 aa) fasta scores: E(): 2.8e-52, 44.97% id in 656 aa, and to Mycobacterium tuberculosis probable serine/threonine-protein kinase PknL or Rv2176 or MT2232 or MTV021.09 SWALL:PKNL_MYCTU (SWALL:O53510) (399 aa) fasta scores: E(): 4e-06, 28.61% id in 318 aa. (720 aa)    
Predicted Functional Partners:
odhI
Putative signal transduction protein; An essential component of the PknG signaling pathway. When unphosphorylated, it inhibits the activity of 2-oxoglutarate dehydrogenase. When phosphorylated it does not inhibit 2-oxoglutarate dehydrogenase (By similarity).
  
 
 
 0.998
DIP2051
Similar to Mycobacterium leprae putative membrane protein MLCB1450.21c SWALL:Q9ZBL6 (EMBL:AL035159) (403 aa) fasta scores: E(): 3.4e-22, 32.51% id in 406 aa, and to Mycobacterium tuberculosis hypothetical 47.1 kDa protein Rv0412c or MT0425 or MTCY22G10.08c SWALL:AAK44649 (EMBL:Z84724) (439 aa) fasta scores: E(): 3.1e-21, 33.09% id in 414 aa.
 
  
 0.985
DIP2052
Putative ABC transpoter membrane protein; Similar to Mycobacterium tuberculosis CDC1551 amino acid ABC transporter, amino acid-binding protein MT0424 SWALL:AAK44648 (EMBL:AE006946) (328 aa) fasta scores: E(): 1.5e-33, 41.84% id in 325 aa, and to Bacillus stearothermophilus glutamine-binding protein precursor GlnH SWALL:GLNH_BACST (SWALL:P27676) (262 aa) fasta scores: E(): 5.3e-19, 31.25% id in 240 aa.
 
  
 0.984
murC
UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
   
  
 0.841
DIP0057
Similar to Mycobacterium leprae probable phosphoprotein phosphatase Ppp TR:Q50188 (EMBL:Z70722) (509 aa) fasta scores: E(): 5.8e-46, 43.64% id in 488 aa.
 
 
 0.827
ftsZ
Cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
      
 0.777
pknB
Similar to Mycobacterium leprae probable serine/threonine-protein kinase PknB or ML0016 SW:PKNB_MYCLE (P54744) (622 aa) fasta scores: E(): 5.7e-58, 43.26% id in 661 aa.
 
 
0.729
DIP2049
Low similarity to Streptomyces coelicolor putative ABC transporter integral membrane protein SCE8.16c SWALL:Q9Z4W1 (EMBL:AL035654) (264 aa) fasta scores: E(): 1.7e-09, 26.37% id in 254 aa.
  
    0.718
DIP0059
Conserved hypothetical protein; Similar to Streptomyces coelicolor hypothetical 30.8 kDa protein SCH69.13 TR:Q9XA21 (EMBL:AL079308) (290 aa) fasta scores: E(): 3.1e-11, 27.6% id in 297 aa.
  
 
 
 0.633
DIP0058
Putative secreted protein; Similar to Mycobacterium leprae hypothetical 17.2 kDa protein MLB1770.14c or ML0021 TR:Q50189 (EMBL:Z70722) (155 aa) fasta scores: E(): 2.3e-13, 35% id in 160 aa.
    
 
 0.626
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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