STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DIP2053Putative protein kinase; Similar to Mycobacterium tuberculosis probable serine/threonine-protein kinase PknG or Rv0410c or MT0423 or MTCY22G10.06c SWALL:PKNG_MYCTU (SWALL:P96256) (750 aa) fasta scores: E(): 2.8e-52, 44.97% id in 656 aa, and to Mycobacterium tuberculosis probable serine/threonine-protein kinase PknL or Rv2176 or MT2232 or MTV021.09 SWALL:PKNL_MYCTU (SWALL:O53510) (399 aa) fasta scores: E(): 4e-06, 28.61% id in 318 aa. (720 aa)    
Predicted Functional Partners:
DIP2051
Similar to Mycobacterium leprae putative membrane protein MLCB1450.21c SWALL:Q9ZBL6 (EMBL:AL035159) (403 aa) fasta scores: E(): 3.4e-22, 32.51% id in 406 aa, and to Mycobacterium tuberculosis hypothetical 47.1 kDa protein Rv0412c or MT0425 or MTCY22G10.08c SWALL:AAK44649 (EMBL:Z84724) (439 aa) fasta scores: E(): 3.1e-21, 33.09% id in 414 aa.
 
  
 0.987
DIP2052
Putative ABC transpoter membrane protein; Similar to Mycobacterium tuberculosis CDC1551 amino acid ABC transporter, amino acid-binding protein MT0424 SWALL:AAK44648 (EMBL:AE006946) (328 aa) fasta scores: E(): 1.5e-33, 41.84% id in 325 aa, and to Bacillus stearothermophilus glutamine-binding protein precursor GlnH SWALL:GLNH_BACST (SWALL:P27676) (262 aa) fasta scores: E(): 5.3e-19, 31.25% id in 240 aa.
 
  
 0.987
odhI
Putative signal transduction protein; An essential component of the PknG signaling pathway. When unphosphorylated, it inhibits the activity of 2-oxoglutarate dehydrogenase. When phosphorylated it does not inhibit 2-oxoglutarate dehydrogenase (By similarity).
  
 
 
 0.969
DIP0057
Similar to Mycobacterium leprae probable phosphoprotein phosphatase Ppp TR:Q50188 (EMBL:Z70722) (509 aa) fasta scores: E(): 5.8e-46, 43.64% id in 488 aa.
 
 
 0.785
DIP2049
Low similarity to Streptomyces coelicolor putative ABC transporter integral membrane protein SCE8.16c SWALL:Q9Z4W1 (EMBL:AL035654) (264 aa) fasta scores: E(): 1.7e-09, 26.37% id in 254 aa.
  
    0.704
murC
UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
   
  
 0.693
ftsZ
Cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
      
 0.691
DIP2050
Similar to Streptomyces coelicolor putative ABC transporter ATP-binding subunit 2SC6G5.39c SWALL:Q9K4B6 (EMBL:AL359152) (346 aa) fasta scores: E(): 9.3e-56, 60% id in 305 aa, and to Bacillus sphaericus CDD4-like protein SWALL:Q9Z5R0 (EMBL:AJ224479) (311 aa) fasta scores: E(): 7.9e-29, 37.45% id in 299 aa.
  
    0.596
DIP2098
Putative secreted protein; No significant database matches.
  
     0.592
DIP2191
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 35.4 kDa protein Rv3802c or MTV026.07c TR:O53581 (EMBL:AL022076) (336 aa) fasta scores: E(): 3.2e-34, 41.32% id in 317 aa.
  
     0.567
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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