STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (399 aa)    
Predicted Functional Partners:
pta
Phosphate acetyltransferase; Highly similar in its C-terminal region to Corynebacterium glutamicum phosphate acetyltransferase Pta SWALL:PTA_CORGL (SWALL:P77844) (329 aa) fasta scores: E(): 6.9e-94, 78.22% id in 326 aa, similar to the C-terminal region of Mycobacterium tuberculosis phosphate acetyltransferase Pta or Rv0408 or MT0421 or MTCY22G10.04 SWALL:PTA_MYCTU (SWALL:P96254) (690 aa) fasta scores: E(): 4.8e-68, 48.67% id in 452 aa, and similar to the C-terminal region of Escherichia coli phosphate acetyltransferase Pta or B2297 SWALL:PTA_ECOLI (SWALL:P39184) (713 aa) fasta scores: [...]
 
 
 0.999
DIP1952
Similar to Escherichia coli pyruvate dehydrogenase [cytochrome] PoxB SW:POXB_ECOLI (P07003) (572 aa) fasta scores: E(): 1.2e-100, 45.89% id in 573 aa, and to Streptomyces coelicolor pyruvate dehydrogenase SC1A9.19 TR:Q9ZBT3 (EMBL:AL034446) (580 aa) fasta scores: E(): 1.4e-132, 56.62% id in 581 aa; Belongs to the TPP enzyme family.
    
 0.952
cat1
Similar to Clostridium kluyveri succinyl-CoA:coenzyme A transferase Cat1 SWALL:CAT1_CLOKL (SWALL:P38946) (538 aa) fasta scores: E(): 1.8e-85, 47.56% id in 513 aa, and to Caulobacter crescentus coenzyme A transferase, putative CC3724 SWALL:Q9A242 (EMBL:AE006030) (514 aa) fasta scores: E(): 1.3e-97, 52.96% id in 506 aa.
     
 0.915
DIP2115
Putative aldehyde dehydrogenase; Similar to many eg. Acinetobacter spM-1. aldehyde dehydrogenase 1 Ald1 TR:Q9FDS1 (EMBL:AB042203) (503 aa) fasta scores: E(): 2.5e-143, 69.18% id in 503 aa, and to Alcaligenes eutrophus acetaldehyde dehydrogenase II AcoD SW:DHA2_ALCEU (P46368) (506 aa) fasta scores: E(): 1.8e-135, 66.39% id in 497 aa.
  
 
 0.913
acyP
Similar to Mycobacterium tuberculosis putative acylphosphatase Rv2922.1c or MT2991 or MTCY338.11bc SW:ACYP_MYCTU (P56543) (93 aa) fasta scores: E(): 1.3e-14, 52.08% id in 96 aa, and to Escherichia coli putative acylphosphatase YccX or B0968 or Z1320 or ECS1052 SW:ACYP_ECOLI (P75877) (92 aa) fasta scores: E(): 1.2e-07, 43.82% id in 89 aa.
     
 0.907
ptsG
Similar to Corynebacterium glutamicum PTS system, glucose-specific IIABC component PtsG SWALL:PTGA_CORGL (SWALL:Q45298) (674 aa) fasta scores: E(): 2.8e-59, 44.91% id in 688 aa, and to Staphylococcus xylosus PTS system, sucrose-specific IIBC component ScrA SWALL:PTSB_STAXY (SWALL:P51184) (480 aa) fasta scores: E(): 8e-26, 27.73% id in 494 aa.
  
  
 0.878
fas
Putative fatty acid synthase; Similar to the N-terminal region of Corynebacterium ammoniagenes fatty acid synthase Fas TR:Q04846 (EMBL:X64795) (3104 aa) fasta scores: E(): 0, 61.33% id in 3018 aa, and to the full length of Mycobacterium tuberculosis fatty acid synthase Rv2524c TR:AAK46907 (EMBL:Z83863) (3069 aa) fasta scores: E(): 1e-197, 51.37% id in 3083 aa, and of Corynebacterium glutamicum 3-oxoacyl-(acyl-carrier-protein) synthase CGL2495 SWALL:Q8NMS0 (EMBL:AP005281) (2993 aa) fasta scores: E(): 0, 67.35% id in 3008 aa.
  
  
 0.771
DIP2056
Similar to Streptomyces coelicolor putative ferredoxin/ferredoxin-NADP reductase SCF15.02 SWALL:Q9RK35 (EMBL:AL132856) (454 aa) fasta scores: E(): 4e-107, 59.95% id in 452 aa, and to Rattus norvegicus NADPH:adrenodoxin oxidoreductase, mitochondrial precursor FdxR SWALL:ADRO_RAT (SWALL:P56522) (494 aa) fasta scores: E(): 1.3e-42, 36.02% id in 458 aa, and to Mycobacterium tuberculosis probable ferredoxin/ferredoxin--NADP reductase FprB or Rv0886 or MT0909 or MTCY31.14 SWALL:FPRB_MYCTU (SWALL:Q10547) (575 aa) fasta scores: E(): 2.1e-33, 35.98% id in 453 aa.
       0.674
gltA
Citrate synthase; Similar to Corynebacterium glutamicum citrate synthase GltA SW:CISY_CORGL (P42457) (437 aa) fasta scores: E(): 2.5e-151, 87.52% id in 433 aa.
   
  
 0.605
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
      
 0.562
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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