STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2056Similar to Streptomyces coelicolor putative ferredoxin/ferredoxin-NADP reductase SCF15.02 SWALL:Q9RK35 (EMBL:AL132856) (454 aa) fasta scores: E(): 4e-107, 59.95% id in 452 aa, and to Rattus norvegicus NADPH:adrenodoxin oxidoreductase, mitochondrial precursor FdxR SWALL:ADRO_RAT (SWALL:P56522) (494 aa) fasta scores: E(): 1.3e-42, 36.02% id in 458 aa, and to Mycobacterium tuberculosis probable ferredoxin/ferredoxin--NADP reductase FprB or Rv0886 or MT0909 or MTCY31.14 SWALL:FPRB_MYCTU (SWALL:Q10547) (575 aa) fasta scores: E(): 2.1e-33, 35.98% id in 453 aa. (452 aa)    
Predicted Functional Partners:
DIP0703
Putative oxidoreductase; Similar to Mycobacterium tuberculosis hypothetical 40.8 kDa protein Rv3230c or MTCY20B11.05c TR:O05875 (EMBL:Z95121) (380 aa) fasta scores: E(): 4.8e-60, 49.14% id in 350 aa, and to Escherichia coli NADH oxidoreductase Hcr or B0872 SW:HCR_ECOLI (P75824) (322 aa) fasta scores: E(): 1.9e-13, 28.71% id in 296 aa.
   
 0.807
fdxA
Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
 
 
 0.784
DIP0137
Conserved hypothetical protein; Similar to a region of Corynebacterium glutamicum Ycg4K TR:Q9EUM3 (EMBL:AF164956) (256 aa) fasta scores: E(): 9.2e-09, 75.61% id in 41 aa.
    
 0.760
DIP0630
Putative methionine biosynthesis-related protein; Similar to Mycobacterium tuberculosis CDC1551 transulfuration enzyme family protein MT3443 TR:AAK47787 (EMBL:AE007151) (449 aa) fasta scores: E(): 4.8e-93, 56.94% id in 432 aa, and to Pseudomonas aeruginosa O-succinylhomoserine sulfhydrylase MetZ or PA3107 SW:METZ_PSEAE (P55218) (403 aa) fasta scores: E(): 2.7e-26, 39.31% id in 435 aa.
   
    0.755
DIP2110
Putative oxidoreductase; Similar to Mycobacterium bovis 47 kDa protein Rv0385 or MT0398 or MTV036.20 TR:O86363 (EMBL:U73653) (390 aa) fasta scores: E(): 4.7e-29, 36.36% id in 352 aa, and to Acinetobacter calcoaceticus phenolhydroxylase component TR:Q43983 (EMBL:Z36909) (350 aa) fasta scores: E(): 2.2e-06, 25.61% id in 246 aa, and to Pseudomonas sp phenol hydroxylase P5 protein DmpP SW:DMPP_PSESP (P19734) (352 aa) fasta scores: E(): 8.3e-06, 24.3% id in 251 aa.
  
 
 0.737
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
       0.674
pta
Phosphate acetyltransferase; Highly similar in its C-terminal region to Corynebacterium glutamicum phosphate acetyltransferase Pta SWALL:PTA_CORGL (SWALL:P77844) (329 aa) fasta scores: E(): 6.9e-94, 78.22% id in 326 aa, similar to the C-terminal region of Mycobacterium tuberculosis phosphate acetyltransferase Pta or Rv0408 or MT0421 or MTCY22G10.04 SWALL:PTA_MYCTU (SWALL:P96254) (690 aa) fasta scores: E(): 4.8e-68, 48.67% id in 452 aa, and similar to the C-terminal region of Escherichia coli phosphate acetyltransferase Pta or B2297 SWALL:PTA_ECOLI (SWALL:P39184) (713 aa) fasta scores: [...]
       0.674
etfB
Similar to Mycobacterium tuberculosis electron transfer flavoprotein beta-subunit FixA or Rv3029c or MT3113 or MTV012.44c SW:ETFB_MYCTU (O53276) (266 aa) fasta scores: E(): 8.4e-45, 51.31% id in 267 aa.
  
 
 0.648
DIP0611
Putative ABC transport system secreted protein; Similar to Escherichia coli lipoprotein-28 precursor NlpA or B3661 SW:NLPA_ECOLI (P04846) (272 aa) fasta scores: E(): 1.5e-20, 33.83% id in 266 aa. Possible duplication of the CDS downstream, CDIP0610 (66.667% identity in 288 aa overlap).
   
    0.485
etfA
Similar to Mycobacterium tuberculosis electron transfer flavoprotein alpha-subunit EtfA or FixB or Rv3028c or MT3112 or MTV012.43c SW:ETFA_MYCTU (O53275) (318 aa) fasta scores: E(): 1.8e-48, 51.1% id in 317 aa.
  
 
 0.477
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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