Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DIP2066Some similarity to Actinomyces naeslundii putative fimbrial associated protein TR:O05995 (EMBL:U85708) (375 aa) fasta scores: E(): 0.0012, 28.803% id in 309 aa. Note: Contains a potential sortase anchor site (LPKTG) upstream of the C-terminal region transmembrane domain. (1080 aa)    
Predicted Functional Partners:
DIP2014
Putative membrane-anchored protein; No significant database matches.
      
 0.618
repA
Putative IS element transposase (pseudogene); Pseudogene. Similar to although shorter in its N-terminal region than Shigella flexneri putative transposase for IS110 S0128 SWALL:Q9AFS5 (EMBL:AF348706) (398 aa) fasta scores: E(): 1.6e-18, 40.55% id in 254 aa, and similar to Streptomyces coelicolor putative IS element transposase SC3C8.17 SWALL:O69929 (EMBL:AL023861) (230 aa) fasta scores: E(): 7.9e-18, 45.61% id in 171 aa. Presents multiple frameshifts at residues 84, 125, 130, 145, 150 and 180.
     
 0.618
DIP0582
Putative iron transport system binding (secreted) protein; Similar to Escherichia coli iron FecB or B4290 SW:FECB_ECOLI (P15028) (300 aa) fasta scores: E(): 1.6e-12, 28.57% id in 287 aa.
  
   
 0.609
DIP2013
Similar to Actinomyces naeslundii fimbrial subunit type 2 precursor SW:FM2_ACTNA (P12616) (534 aa) fasta scores: E(): 4.4e-20, 28.827% id in 503 aa, and to Actinomyces naeslundii type-1 fimbrial major subunit precursor FimP TR:Q9X4D8 (EMBL:AF107019) (533 aa) fasta scores: E(): 8.5e-15, 27.432% id in 514 aa. Note: Contains a potential sortase anchor site (LPLTG) upstream of the C-terminal region transmembrane domain.
  
     0.479
DIP0233
Similar to Actinomyces naeslundii putative fimbrial associated protein TR:O05996 (EMBL:U85709) (280 aa) fasta scores: E(): 4.5e-16, 40.000% id in 215 aa, and to Staphylococcus aureus sortase SrtA TR:Q9S446 (EMBL:AF162687) (206 aa) fasta scores: E(): 1.2, 26.923% id in 156 aa. Note: Also similar to DIP0236 (312 aa) E(): 5.7e-25; 45.342% identity in 322 aa overlap, DIP2224, DIP2012 and DIP2225.
  
     0.461
DIP0236
Similar to Actinomyces naeslundii putative fimbrial associated protein TR:O68213 (EMBL:AF019629) (365 aa) fasta scores: E(): 1.2e-31, 42.802% id in 257 aa, and to Staphylococcus aureus sortase SrtA TR:Q9S446 (EMBL:AF162687) (206 aa) fasta scores: E(): 0.094, 27.559% id in 127 aa. Note: Also similar to DIP0233 (329 aa) E(): 5.2e-25; 45.031% identity in 322 aa overlap. Note: Also similar to DIP2012, DIP2224 and DIP2225.
  
     0.460
DIP1081
Putative acetyltransferase; Similar to Bacillus halodurans ribosomal-protein (S18)-alanine acetyltransferase BH0547 TR:Q9KFD4 (EMBL:AP001508) (151 aa) fasta scores: E(): 0.0026, 52.83% id in 53 aa, and to Homo sapiens similar to spermidine/spermine N1-acetyl transferase TR:AAH11751 (EMBL:BC011751) (170 aa) fasta scores: E(): 0.0061, 28.85% id in 149 aa.
  
     0.453
DIP1937
Putative exported protein; Poor database matches. Similar to the C-terminal region of Bacillus subtilis extracellular metalloprotease precursor Mpr SW:MPR_BACSU (P39790) (313 aa) fasta scores: E(): 8.9, 23.76% id in 202 aa.
  
   0.448
DIP2012
Putative fimbrial associated sortase-like protein; Similar to Actinomyces viscosus sortase-like protein SWALL:Q9AJ92 (EMBL:AF106034) (387 aa) fasta scores: E(): 2.7e-39, 43.47% id in 276 aa, and to Bifidobacterium longum NCC2705 sortase-like protein BL0676 SWALL:AAN24497 (EMBL:AE014690) (328 aa) fasta scores: E(): 3.7e-28, 36.94% id in 268 aa, and to Streptococcus pneumoniae sortase, putative SP0466 SWALL:AAK74626 (EMBL:AE007358) (279 aa) fasta scores: E(): 3e-21, 31.78% id in 258 aa.
  
     0.442
DIP0235
Putative fimbrial subunit; Similar to Actinomyces viscosus type-1 fimbrial major subunit precursor FimP TR:Q9X4D1 (EMBL:AF106034) (535 aa) fasta scores: E(): 6.9e-16, 31.5% id in 530 aa. Note: Contains a potential sortase anchor site (LTMPG) upstream of the C-terminal region transmembrane domain.
  
     0.426
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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