Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DIP2079Similar to many putative oxidoreductases e.g. Rhizobium meliloti putative oxidoreductase protein R01702 or SMC00274 SWALL:CAC46281 (EMBL:AL591788) (295 aa) fasta scores: E(): 7.6e-30, 41.4% id in 285 aa, and to Escherichia coli hypothetical oxidoreductase YgbJ or B2736 SWALL:YGBJ_ECOLI (SWALL:Q46888) (302 aa) fasta scores: E(): 2e-26, 36.08% id in 291 aa. (298 aa)    
Predicted Functional Partners:
DIP2080
Similar to Synechocystis sp hypothetical 48.5 kDa protein SLR1342 SWALL:P74079 (EMBL:D90912) (445 aa) fasta scores: E(): 2.4e-39, 34.19% id in 462 aa.
  
 0.993
DIP1811
Similar to Rhizobium loti dehydrogenase; zinc-binding alcohol dehydrogenase; NADPH quinone oxidoreductase; oxidoreductase MLR3212 TR:Q98GR0 (EMBL:AP003001) (329 aa) fasta scores: E(): 4.7e-52, 47.67% id in 323 aa, and to Pseudomonas aeruginosa probable oxidoreductase PA1833 TR:Q9I2R2 (EMBL:AE004609) (330 aa) fasta scores: E(): 5.9e-45, 43.82% id in 324 aa.
  
  
  0.835
accBC
Similar to Corynebacterium glutamicum acyl coenzyme A carboxylase AccBC TR:P71122 (EMBL:U35023) (591 aa) fasta scores: E(): 1.5e-188, 85.47% id in 592 aa, and to Mycobacterium leprae acetyl-/propionyl-coenzyme A carboxylase alpha chain [includes: biotin carboxylase (EC 6.3.4.14); biotin carboxyl carrier protein(BCCP)] BccA or ML0726 or B1308_C1_129 SW:BCCA_MYCLE (P46392) (598 aa) fasta scores: E(): 1.1e-159, 72.46% id in 592 aa.
  
 
 0.827
pccB1
Propionyl CoA carboxylase beta chain 1; Similar to Corynebacterium glutamicum DtsR2 protein TR:O87201 (EMBL:AB018531) (537 aa) fasta scores: E(): 2e-182, 87.87% id in 536 aa, and to Saccharopolyspora erythraea propionyl-CoA carboxylase beta chain PccB SW:PCCB_SACER (P53003) (546 aa) fasta scores: E(): 5.2e-137, 64.83% id in 546 aa. Possible duplication of DIP0660 (69.309% identity in 492 aa overlap).
   
 
  0.801
pccB2
propionyl-CoA carboxylase beta chain 2; Similar to Corynebacterium glutamicum DtsR1 protein TR:O88155 (EMBL:AB018531) (543 aa) fasta scores: E(): 1.5e-173, 81.76% id in 543 aa, and to Saccharopolyspora erythraea propionyl-CoA carboxylase beta chain PccB SW:PCCB_SACER (P53003) (546 aa) fasta scores: E(): 2.7e-127, 59.89% id in 546 aa. Possible duplication of DIP0658 (69.309% identity in 492 aa overlap).
   
 
  0.801
DIP0657
Hypothetical protein; No significant database matches.
     
  0.800
pycB
Similar to Methanococcus jannaschii pyruvate carboxylase subunit B PycB or MJ1231 SW:PYCB_METJA (Q58628) (567 aa) fasta scores: E(): 1.8e-88, 50.81% id in 490 aa, and to Propionibacterium freudenreichii shermanii biotin carboxyl carrier protein of methylmalonyl-CoA carboxyl-transferase TR:Q05618 (EMBL:L06488) (519 aa) fasta scores: E(): 1.2e-108, 66.15% id in 520 aa.
     
  0.800
DIP0885
Putative hydrolase; Similar to Rhizobium loti 3-hydroxyisobutyryl-coenzyme A hydrolase MLR8392 TR:Q983C3 (EMBL:AP003014) (347 aa) fasta scores: E(): 3.8e-34, 36.47% id in 329 aa.
  
 0.800
pta
Phosphate acetyltransferase; Highly similar in its C-terminal region to Corynebacterium glutamicum phosphate acetyltransferase Pta SWALL:PTA_CORGL (SWALL:P77844) (329 aa) fasta scores: E(): 6.9e-94, 78.22% id in 326 aa, similar to the C-terminal region of Mycobacterium tuberculosis phosphate acetyltransferase Pta or Rv0408 or MT0421 or MTCY22G10.04 SWALL:PTA_MYCTU (SWALL:P96254) (690 aa) fasta scores: E(): 4.8e-68, 48.67% id in 452 aa, and similar to the C-terminal region of Escherichia coli phosphate acetyltransferase Pta or B2297 SWALL:PTA_ECOLI (SWALL:P39184) (713 aa) fasta scores: [...]
     
  0.800
DIP2078
Putative membrane transport protein; Similar to Corynebacterium glutamicum gluconate permease GntP SWALL:Q9AL75 (EMBL:AJ296014) (463 aa) fasta scores: E(): 3.8e-50, 36.3% id in 449 aa, and to Escherichia coli Gnt-II system L-idonate transporter IdnT or GntW or B4265 SWALL:IDNT_ECOLI (SWALL:P39344) (439 aa) fasta scores: E(): 3.4e-44, 31.98% id in 444 aa, and to Escherichia coli high-affinity gluconate transporter GntP or B4321 or Z5919 or ECS5280 SWALL:GNTP_ECOLI (SWALL:P39373) (447 aa) fasta scores: E(): 5.1e-39, 31.49% id in 435 aa.
     
 0.800
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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