STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2095Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 fructose-bisphosphate aldolase family protein MT0381 SWALL:AAK44602 (EMBL:AE006943) (376 aa) fasta scores: E(): 7.2e-55, 43.61% id in 376 aa, and to Corynebacterium glutamicum hypothetical protein in fda 5' region SWALL:Q99336 (EMBL:X17313) (304 aa) fasta scores: E(): 1.6e-37, 60.55% id in 289 aa. (375 aa)    
Predicted Functional Partners:
DIP2096
Putative RNA methylase family protein; Similar to although shoter in its N-terminal region than Mycobacterium tuberculosis CDC1551 SpoU rRNA methylase family protein MT0393 SWALL:AAK44615 (EMBL:AE006944) (183 aa) fasta scores: E(): 6.2e-51, 74.41% id in 172 aa, and to Escherichia coli tRNA TrmH or SpoU or B3651 or Z5077 or ECS4526 SWALL:TRMH_ECOLI (SWALL:P19396) (229 aa) fasta scores: E(): 4.6e-07, 28.94% id in 152 aa.
       0.835
DIP1613
Putative membrane protein; Similar to Mycobacterium tuberculosis putative membrane protein Rv2174 or MTV021.07 TR:O53508 (EMBL:AL021957) (516 aa) fasta scores: E(): 2.2e-56, 34.69% id in 464 aa.
  
     0.736
DIP2098
Putative secreted protein; No significant database matches.
 
     0.722
DIP1297
Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 62.7 kDa protein Rv1459c or MT1506 or MTV007.06c SWALL:AAK45770 (EMBL:AL021184) (591 aa) fasta scores: E(): 2.6e-33, 36.63% id in 546 aa, and to Mycobacterium tuberculosis putative membrane protein Rv2174 or MT2230 or MTV021.07 SWALL:O53508 (EMBL:AL021957) (516 aa) fasta scores: E(): 2.1e-18, 30.6% id in 464 aa, and low similarity to Rhizobium meliloti putative cytochrome C oxidase polypeptide I transmembrane protein CtaD or R00905 or SMC00010 SWALL:Q92RG9 (EMBL:AL591785) (562 aa) fasta scores: E(): 1.6, 22.9 [...]
  
     0.717
fba
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
       0.673
DIP1137
Putative biotin carboxyl carrier protein; Similar to C-terminus of Mycobacterium smegmatis pyruvate carboxylase Pyc TR:Q9F843 (EMBL:AF262949) (1127 aa) fasta scores: E(): 1.9e-05, 47.761% id in 67 aa, to Bacillus subtilis YngXX TR:Q9R9I3 (EMBL:AF184956) (73 aa) fasta scores: E(): 0.0043, 36.765% id in 68 aa, and to Propionibacterium freudenreichii shermanii biotin carboxyl carrier protein of methylmalonyl-CoA carboxyl- transferase SW:BCCP_PROFR (P02904) (123 aa) fasta scores: E(): 0.0079, 38.806% id in 67 aa.
  
     0.654
pyrE
Phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
       0.654
DIP1132
Putative exported protein; Similar to Mycobacterium leprae possible secreted protein ML1677 TR:Q9CBS1 (EMBL:AL583923) (191 aa) fasta scores: E(): 8.9e-13, 32.447% id in 188 aa, and to Mycobacterium tuberculosis hypothetical 18.8 kDa protein Rv2980 or MTCY349.07c TR:P95115 (EMBL:Z83018) (181 aa) fasta scores: E(): 1.5e-09, 31.098% id in 164 aa.
  
     0.648
DIP0716
Putative secreted protein; Low similarity to Mycobacterium leprae putative membrane protein ML0810 TR:Q9CCH4 (EMBL:AL583919) (407 aa) fasta scores: E(): 1.1e-21, 26.81% id in 414 aa.
  
     0.636
DIP0567
Similar to Mycobacterium leprae hypothetical protein ML0370 TR:Q9CCV6 (EMBL:AL583918) (289 aa) fasta scores: E(): 6.4e-34, 42.46% id in 252 aa.
  
     0.635
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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