STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
DIP2129Putative binding-protein-dependent integral membrane transport protein; Similar to Mycobacterium tuberculosis putative phosphate permease Rv2281 or MT2339 or MTCY339.29C SW:YM81_MYCTU (Q50684) (552 aa) fasta scores: E(): 1.2e-121, 61% id in 518 aa. (528 aa)    
Predicted Functional Partners:
lysG
Similar to Corynebacterium glutamicum lysine export transcriptional regulatory protein LysG SW:LYSG_CORGL (P94632) (290 aa) fasta scores: E(): 3.2e-70, 62.54% id in 291 aa, and to Streptomyces coelicolor putative LysR-family transcriptional regulator SC5F8.17c TR:Q9K4K7 (EMBL:AL357613) (300 aa) fasta scores: E(): 3.8e-43, 46.8% id in 297 aa, and to Rhodococcus fascians AttR protein TR:CAC43333 (EMBL:AJ311775) (320 aa) fasta scores: E(): 2.2e-37, 43.43% id in 297 aa.
      
 0.671
lysE
Lysine exporter protein; Catalyzes the efflux of L-lysine. Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
      
 0.529
DIP1910
Putative phosphate-binding periplasmic protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.
     
 0.526
hemA
Putative glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
      
 0.506
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
      
 0.506
DIP1615
Similar to Streptomyces coelicolor eukaryotic-type protein kinase PkaF TR:Q9ZNB3 (EMBL:AB019394) (629 aa) fasta scores: E(): 8.2e-37, 36.22% id in 646 aa.
      
 0.503
pknA
Similar to Mycobacterium leprae probable serine/threonine-protein kinase PnkA or ML0017 SW:PKNA_MYCLE (P54743) (437 aa) fasta scores: E(): 4e-37, 41.99% id in 431 aa.
      
 0.501
DIP0411
Putative electron transport related protein; Similar to Deinococcus radiodurans thiol:disulfide interchange protein DR0189 TR:Q9RXW6 (EMBL:AE001881) (185 aa) fasta scores: E(): 7.1e-09, 34.84% id in 132 aa, and to Bacillus halodurans thioredoxin BH1522 TR:Q9KCP7 (EMBL:AP001512) (177 aa) fasta scores: E(): 3.4e-08, 34.12% id in 126 aa and to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT0548 TR:AAK44771 (EMBL:AE006954) (216 aa) fasta scores: E(): 9.2e-31, 48.95% id in 192 aa.
      
 0.494
DIP2126
Similar to Streptomyces coelicolor putative transport permease protein SC9B5.20 TR:Q9ZBG0 (EMBL:AL035206) (312 aa) fasta scores: E(): 4.4e-32, 45.27% id in 254 aa, and to Bacillus subtilis dipeptide transport system permease protein DppC or DciAC SW:DPPC_BACSU (P26904) (320 aa) fasta scores: E(): 4.3e-23, 37.19% id in 242 aa.
     
 0.450
DIP2125
Similar to Streptomyces coelicolor putative ABC transporter ATP-binding protein SC9B5.22 TR:Q9ZBF8 (EMBL:AL035206) (222 aa) fasta scores: E(): 7.5e-19, 41.66% id in 216 aa, and to Escherichia coli nickel transport ATP-binding protein NikE or B3480 SW:NIKE_ECOLI (P33594) (268 aa) fasta scores: E(): 6.3e-17, 38.72% id in 204 aa.
       0.444
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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