STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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[Homology]
Score
DIP2131Conserved hypothetical protein; Similar to Rhizobium meliloti putative MTA/SHA nucleosidase p46 includes: 5'-methylthioadenosine nucleosidase and s-adenosylhomocysteine nucleosidase protein Pfs or r00315 or smc00395 TR:CAC41752 (EMBL:AL591783) (212 aa) fasta scores: E(): 1e-08, 30.68% id in 176 aa. (196 aa)    
Predicted Functional Partners:
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
 0.912
DIP1594
Conserved hypothetical protein; Similar to Corynebacterium glutamicum hypothetical 26.0 kDa protein in FtsZ 3'region SW:YFTZ_CORGL (P94338) (246 aa) fasta scores: E(): 6.5e-66, 68.72% id in 243 aa, and to Streptomyces griseus hypothetical 25.3 kDa protein in FtsZ 3'region SW:YFTZ_STRGR (P45496) (246 aa) fasta scores: E(): 7.4e-41, 50% id in 228 aa; Belongs to the multicopper oxidase YfiH/RL5 family.
    
  0.900
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.560
DIP2132
Putative oxidoreductase; Weakly similar to Rattus norvegicus NADPH:adrenodoxin oxidoreductase, mitochondrial precursor FdxR SW:ADRO_RAT (P56522) (494 aa) fasta scores: E(): 0.002, 28.3% id in 159 aa, and to Streptomyces coelicolor putative ferredoxin/ferredoxin-NADP reductase SCF15.02 TR:Q9RK35 (EMBL:AL132856) (454 aa) fasta scores: E(): 0.048, 29% id in 131 aa.
       0.555
DIP2058
Similar to Streptomyces coelicolor putative purine phosphoribosyltransferase SCH35.47 SWALL:Q9X8V9 (EMBL:AL078610) (165 aa) fasta scores: E(): 1.1e-27, 52.25% id in 155 aa, and to Aeropyrum pernix 272aa long hypothetical hypoxanthine phosphoribosyltransferase APE2071 SWALL:Q9YA68 (EMBL:AP000063) (272 aa) fasta scores: E(): 3.8e-16, 36.47% id in 159 aa.
    
  0.525
DIP2133
Putative conserved membrane protein; Similar to many eg. Mycobacterium tuberculosis hypothetical 95.5 kDa protein Rv0338c or MT0352 or MTCY279.05C TR:O33268 (EMBL:Z97991) (882 aa) fasta scores: E(): 2.4e-55, 43.1% id in 877 aa. N-terminal region appears to be has possible membrane-spanning hydrophobic regions while the C-terminal region is rich in proline and alanine.
 
     0.511
fas
Putative fatty acid synthase; Similar to the N-terminal region of Corynebacterium ammoniagenes fatty acid synthase Fas TR:Q04846 (EMBL:X64795) (3104 aa) fasta scores: E(): 0, 61.33% id in 3018 aa, and to the full length of Mycobacterium tuberculosis fatty acid synthase Rv2524c TR:AAK46907 (EMBL:Z83863) (3069 aa) fasta scores: E(): 1e-197, 51.37% id in 3083 aa, and of Corynebacterium glutamicum 3-oxoacyl-(acyl-carrier-protein) synthase CGL2495 SWALL:Q8NMS0 (EMBL:AP005281) (2993 aa) fasta scores: E(): 0, 67.35% id in 3008 aa.
  
 
 0.505
hpt
Similar to Vibrio harveyi hypoxanthine phosphoribosyltransferase Hpt SW:HPRT_VIBHA (P18134) (176 aa) fasta scores: E(): 5.3e-28, 48.21% id in 168 aa, and to Mycobacterium leprae hypoxanthine-guanine phosphoribosyltransferase ML0214 SW:HPRT_MYCLE (O69537) (203 aa) fasta scores: E(): 3.2e-40, 55.31% id in 188 aa; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
    
  0.504
deoD
Putative transposase (pseudogene); Possible inverted repeat.
     
  0.500
DIP0274
Putative mutase; Similar to Streptomyces coelicolor putative phosphomannomutase SCK13.08c TR:Q9AD82 (EMBL:AL512667) (549 aa) fasta scores: E(): 7.9e-86, 46.75% id in 554 aa.
     
  0.500
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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