STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2133Putative conserved membrane protein; Similar to many eg. Mycobacterium tuberculosis hypothetical 95.5 kDa protein Rv0338c or MT0352 or MTCY279.05C TR:O33268 (EMBL:Z97991) (882 aa) fasta scores: E(): 2.4e-55, 43.1% id in 877 aa. N-terminal region appears to be has possible membrane-spanning hydrophobic regions while the C-terminal region is rich in proline and alanine. (834 aa)    
Predicted Functional Partners:
DIP1031
Similar to Streptomyces coelicolor putative iron-sulfur protein SCF43A.06 TR:Q9XAA9 (EMBL:AL096837) (492 aa) fasta scores: E(): 9.1e-97, 57.35% id in 483 aa, and to Escherichia coli putative electron transport protein YkgF or B0307 SW:YKGF_ECOLI (P77536) (475 aa) fasta scores: E(): 5.4e-64, 39.41% id in 482 aa.
  
 
 0.768
DIP2134
Conserved hypothetical protein; N-terminus similar to those from other actinomycetes eg. Saccharopolyspora erythraea Orf122 protein TR:Q54106 (EMBL:X92556) (121 aa) fasta scores: E(): 0.0076, 31.15% id in 138 aa, and to Streptomyces coelicolor hypothetical 30.8 kDa protein SCE6.30c TR:Q9KZR0 (EMBL:AL353832) (277 aa) fasta scores: E(): 0.02, 36.76% id in 68 aa.
       0.708
DIP1030
Conserved hypothetical protein; Similar to Streptomyces coelicolor hypothetical 23.2 kDa protein SCF43A.07 TR:Q9XAA8 (EMBL:AL096837) (215 aa) fasta scores: E(): 3.3e-26, 44.65% id in 215 aa, and to Deinococcus radiodurans conserved hypothetical protein DR1909 TR:Q9RT57 (EMBL:AE002030) (212 aa) fasta scores: E(): 7.8e-17, 37.44% id in 211 aa.
  
 
 0.700
DIP2132
Putative oxidoreductase; Weakly similar to Rattus norvegicus NADPH:adrenodoxin oxidoreductase, mitochondrial precursor FdxR SW:ADRO_RAT (P56522) (494 aa) fasta scores: E(): 0.002, 28.3% id in 159 aa, and to Streptomyces coelicolor putative ferredoxin/ferredoxin-NADP reductase SCF15.02 TR:Q9RK35 (EMBL:AL132856) (454 aa) fasta scores: E(): 0.048, 29% id in 131 aa.
       0.622
DIP2131
Conserved hypothetical protein; Similar to Rhizobium meliloti putative MTA/SHA nucleosidase p46 includes: 5'-methylthioadenosine nucleosidase and s-adenosylhomocysteine nucleosidase protein Pfs or r00315 or smc00395 TR:CAC41752 (EMBL:AL591783) (212 aa) fasta scores: E(): 1e-08, 30.68% id in 176 aa.
 
     0.531
DIP0372
Similar to Bacillus subtilis succinate dehydrogenase iron-sulfur protein SdhB SWALL:DHSB_BACSU (SWALL:P08066) (252 aa) fasta scores: E(): 1.3e-08, 27.45% id in 255 aa, and to Escherichia coli succinate dehydrogenase iron-sulfur protein SdhB or B0724 SWALL:DHSB_ECOLI (SWALL:P07014) (238 aa) fasta scores: E(): 6.8e-08, 29.43% id in 248 aa.
  
   0.522
etfB
Similar to Mycobacterium tuberculosis electron transfer flavoprotein beta-subunit FixA or Rv3029c or MT3113 or MTV012.44c SW:ETFB_MYCTU (O53276) (266 aa) fasta scores: E(): 8.4e-45, 51.31% id in 267 aa.
 
  
 0.517
etfA
Similar to Mycobacterium tuberculosis electron transfer flavoprotein alpha-subunit EtfA or FixB or Rv3028c or MT3112 or MTV012.43c SW:ETFA_MYCTU (O53275) (318 aa) fasta scores: E(): 1.8e-48, 51.1% id in 317 aa.
 
  
 0.491
glpD
Similar to Mycobacterium leprae glycerol-3-phosphate dehydrogenase GlpD or ML0713 or L308_C1_179 SW:GLPD_MYCLE (P53435) (585 aa) fasta scores: E(): 5.7e-116, 55.35% id in 560 aa, and to Escherichia coli aerobic glycerol-3-phosphate dehydrogenase GlpD or GlyD or B3426 SW:GLPD_ECOLI (P13035) (501 aa) fasta scores: E(): 2.4e-38, 33.67% id in 493 aa.
 
  
 0.426
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: medium (56%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.